7D1V

Hsp90 alpha N-terminal domain in complex with a 6C compund

Summary for 7D1V

Entry DOI	10.2210/pdb7d1v/pdb
Descriptor	Heat shock protein HSP 90-alpha, 6-chloranyl-9-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]purin-2-amine (3 entities in total)
Functional Keywords	chaperone-inhibitor complex, chaperone/inhibitor
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	24694.72
Authors	Shin, S.C.,Kim, E.E. (deposition date: 2020-09-15, release date: 2021-07-28, Last modification date: 2023-11-29)
Primary citation	Shin, S.C.,El-Damasy, A.K.,Lee, J.H.,Seo, S.H.,Kim, J.H.,Seo, Y.H.,Lee, Y.,Yu, J.H.,Bang, E.K.,Kim, E.E.,Keum, G. Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 33317068 DOI: 10.3390/ijms21249377 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.332 Å)

Structure validation