6X3M

Crystal structure of full-length Streptococcal bacteriophage hyaluronidase in complex with unsaturated hyaluronan octa-saccharides

Summary for 6X3M

• Entry DOI: 10.2210/pdb6x3m/pdb
• Related: 6WV2 6WWX 6WXA
• Descriptor: Hyaluronoglucosaminidase, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: hylp, lyase, hyaluronidase, s. pyogenes phage h4489a, beta-elimination, unsaturated hyaluronan octa-saccharides
• Biological source: Streptococcus pyogenes phage H4489A
• Total number of polymer chains: 9
• Total formula weight: 386285.00

Authors

Deivanayagam, C.,Schormann, N. (deposition date: 2020-05-21, release date: 2021-06-09, Last modification date: 2023-10-18)

• Primary citation: Lee, J.H.,Schormann, N.,Rajashankar, K.R.,Deivanaygam, C.; Crystal Structure of Streptococcal Bacteriophage Hyaluronidase: Presence of a Prokaryotic Collagen and Elucidation of Catalytic Mechanism; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.581 Å)