5F1G

Crystal structure of AmpC BER adenylylated in the cytoplasm

Summary for 5F1G

• Entry DOI: 10.2210/pdb5f1g/pdb
• Related: 5F1F
• Descriptor: Beta-lactamase, ADENOSINE MONOPHOSPHATE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: class c beta lactamase, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 41123.45

Authors

An, Y.J.,Kim, M.K.,Na, J.H.,Cha, S.S. (deposition date: 2015-11-30, release date: 2016-12-07, Last modification date: 2024-10-23)

Primary citation

Kim, M.K.,An, Y.J.,Na, J.H.,Seol, J.H.,Ryu, J.Y.,Lee, J.W.,Kang, L.W.,Chung, K.M.,Lee, J.H.,Moon, J.H.,Lee, J.S.,Cha, S.S.
Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine.
J.Antimicrob.Chemother., 72:735-743, 2017

PubMed Abstract: : Investigation into the adenylylation of the nucleophilic serine in AmpC BER and CMY-10 extended-spectrum class C β-lactamases.

PubMed: 27999057
DOI: 10.1093/jac/dkw491

Experimental method

X-RAY DIFFRACTION (1.76 Å)