5GZW

Crystal structure of AmpC BER adenylylated by acetyl-AMP

Summary for 5GZW

• Entry DOI: 10.2210/pdb5gzw/pdb
• Descriptor: Beta-lactamase, ADENOSINE MONOPHOSPHATE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: beta-lactamase, class c, ampc, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 81902.57

Authors

An, Y.J.,Cha, S.S. (deposition date: 2016-10-02, release date: 2017-10-11, Last modification date: 2023-11-08)

• Primary citation: Kim, M.K.,An, Y.J.,Na, J.H.,Seol, J.H.,Ryu, J.Y.,Lee, J.W.,Kang, L.W.,Chung, K.M.,Lee, J.H.,Moon, J.H.,Lee, J.S.,Cha, S.S.; Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine.; J.Antimicrob.Chemother., 72:735-743, 2017; PubMed: 27999057; DOI: 10.1093/jac/dkw491

Experimental method

X-RAY DIFFRACTION (1.489 Å)