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6WTF
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BU of 6wtf by Molmil
Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound
Descriptor: COBALAMIN, IRON/SULFUR CLUSTER, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, ...
Authors:Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J.
Deposit date:2020-05-02
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
6XPA
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BU of 6xpa by Molmil
ScoE with oxovanadium and the CABA substrate bound and His299 and Arg157 flipped out
Descriptor: (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, ACETATE ION, CHLORIDE ION, ...
Authors:Jonnalagadda, R, Drennan, C.L.
Deposit date:2020-07-08
Release date:2021-01-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase.
J.Biol.Chem., 296, 2021
6XO3
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BU of 6xo3 by Molmil
ScoE with alpha-ketoglutarate in an off-site
Descriptor: 2-OXOGLUTARIC ACID, CHLORIDE ION, FE (II) ION, ...
Authors:Jonnalagadda, R, Drennan, C.L.
Deposit date:2020-07-06
Release date:2021-01-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase.
J.Biol.Chem., 296, 2021
6XN6
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BU of 6xn6 by Molmil
ScoE with the CABA substrate bound and His299 and Arg157 flipped out
Descriptor: (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, ACETATE ION, CHLORIDE ION, ...
Authors:Jonnalagadda, R, Drennan, C.L.
Deposit date:2020-07-02
Release date:2021-01-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase.
J.Biol.Chem., 296, 2021
6XOJ
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BU of 6xoj by Molmil
ScoE with the CABA substrate bound and alpha-ketoglutarate in an off-site
Descriptor: (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, 2-OXOGLUTARIC ACID, ACETATE ION, ...
Authors:Jonnalagadda, R, Drennan, C.L.
Deposit date:2020-07-07
Release date:2021-01-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase.
J.Biol.Chem., 296, 2021
6X5K
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BU of 6x5k by Molmil
Crystal structure of CODH/ACS with carbon monoxide bound to the A-cluster
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CARBON MONOXIDE, Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, ...
Authors:Cohen, S.E, Wittenborn, E.C, Hendrickson, R, Drennan, C.L.
Deposit date:2020-05-26
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase
Acs Catalysis, 10, 2020
6N2N
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BU of 6n2n by Molmil
Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from Magnetococcus marinus
Descriptor: IRON/SULFUR CLUSTER, MAGNESIUM ION, Pyruvate ferredoxin/flavodoxin oxidoreductase, ...
Authors:Chen, P.Y.-T, Drennan, C.L.
Deposit date:2018-11-13
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.937 Å)
Cite:A reverse TCA cycle 2-oxoacid:ferredoxin oxidoreductase that makes C-C bonds from CO2.
Joule, 3, 2019
6MSO
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BU of 6mso by Molmil
Crystal structure of mitochondrial fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate
Descriptor: (2S)-2-sulfanylbutanedioic acid, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R, Drennan, C.L, Nonato, M.C.
Deposit date:2018-10-17
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14, 2019
6MSN
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BU of 6msn by Molmil
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate
Descriptor: (2S)-2-sulfanylbutanedioic acid, IRON/SULFUR CLUSTER, fumarate hydratase
Authors:Feliciano, P.R, Drennan, C.L, Nonato, M.C.
Deposit date:2018-10-17
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.591 Å)
Cite:Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14, 2019
6ND3
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BU of 6nd3 by Molmil
wild-type choline TMA lyase in complex with betaine aldehyde
Descriptor: BETAINE ALDEHYDE, Choline trimethylamine-lyase
Authors:Funk, M.A, Drennan, C.L.
Deposit date:2018-12-13
Release date:2019-01-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.364 Å)
Cite:Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria.
J.Am.Chem.Soc., 141, 2019
6NX0
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BU of 6nx0 by Molmil
Crystal structure of the diheme peroxidase BthA from Burkholderia thailandensis E264
Descriptor: CHLORIDE ION, Di-haem cytochrome c peroxidase family protein, GLYCEROL, ...
Authors:Cohen, S.E, Drennan, C.L.
Deposit date:2019-02-07
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state.
Nat Commun, 10, 2019
6NHL
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BU of 6nhl by Molmil
Crystal structure of QueE from Escherichia coli
Descriptor: 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, FE (III) ION, ...
Authors:Grell, T.A.J, Bell, B.N, Nguyen, C, Dowling, D.P, Drennan, C.L.
Deposit date:2018-12-23
Release date:2019-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Protein Sci., 28, 2019
6UNZ
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BU of 6unz by Molmil
Crystal structure of cytosolic fumarate hydratase from Leishmania major
Descriptor: GLYCEROL, IRON/SULFUR CLUSTER, fumarate hydratase 2
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-14
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.195 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6N2O
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BU of 6n2o by Molmil
2-oxoglutarate:ferredoxin oxidoreductase from Magnetococcus marinus with 2-oxoglutarate, coenzyme A and succinyl-CoA bound
Descriptor: 2-OXOGLUTARIC ACID, COENZYME A, IRON/SULFUR CLUSTER, ...
Authors:Chen, P.Y.-T, Drennan, C.L.
Deposit date:2018-11-13
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.824 Å)
Cite:A reverse TCA cycle 2-oxoacid:ferredoxin oxidoreductase that makes C-C bonds from CO2.
Joule, 3, 2019
6OND
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BU of 6ond by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase produced without CooC, reduced
Descriptor: CHLORIDE ION, Carbon monoxide dehydrogenase, FE (III) ION, ...
Authors:Wittenborn, E.C, Cohen, S.E, Drennan, C.L.
Deposit date:2019-04-21
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.723 Å)
Cite:Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.
J.Biol.Chem., 294, 2019
6UQB
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BU of 6uqb by Molmil
Crystal structure of R471A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate and malonate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-18
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UQL
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BU of 6uql by Molmil
Crystal structure of R471A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6V59
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BU of 6v59 by Molmil
Crystal structure of the diheme peroxidase BthA Y463M variant from Burkholderia thailandensis E264
Descriptor: CHLORIDE ION, Di-haem cytochrome c peroxidase family protein, GLYCEROL, ...
Authors:Cohen, S.E, Drennan, C.L.
Deposit date:2019-12-03
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.593 Å)
Cite:A Stable Ferryl Porphyrin at the Active Site of Y463M BthA.
J.Am.Chem.Soc., 142, 2020
6UOI
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BU of 6uoi by Molmil
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
Descriptor: FE (III) ION, FE3-S4 CLUSTER, Fumarate hydratase 2, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-15
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6ONS
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BU of 6ons by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase with the D-cluster ligating cysteines mutated to alanines, coexpressed with CooC, as-isolated
Descriptor: Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, IRON/SULFUR CLUSTER
Authors:Cohen, S.E, Wittenborn, E.C, Drennan, C.L.
Deposit date:2019-04-22
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.
J.Biol.Chem., 294, 2019
6ONC
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BU of 6onc by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase produced without CooC, as-isolated
Descriptor: CHLORIDE ION, Carbon monoxide dehydrogenase, FE (III) ION, ...
Authors:Wittenborn, E.C, Cohen, S.E, Drennan, C.L.
Deposit date:2019-04-21
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.
J.Biol.Chem., 294, 2019
6UQN
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BU of 6uqn by Molmil
Crystal structure of R173A variant of cytosolic fumarate hydratase from Leishmania major in a complex with fumarate and S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, FUMARIC ACID, Fumarate hydratase 2, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UOJ
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BU of 6uoj by Molmil
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with succinate
Descriptor: Fumarate hydratase 2, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-15
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UPM
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BU of 6upm by Molmil
Crystal structure of T467A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase 2, GLYCEROL, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-17
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6UP9
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BU of 6up9 by Molmil
Crystal structure of T467A variant of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
Descriptor: Fumarate hydratase 2, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2019-10-16
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019

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PDB entries from 2024-09-18

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