6ND3

wild-type choline TMA lyase in complex with betaine aldehyde

Summary for 6ND3

Entry DOI	10.2210/pdb6nd3/pdb
Descriptor	Choline trimethylamine-lyase, BETAINE ALDEHYDE (3 entities in total)
Functional Keywords	radical, lyase, barrel
Biological source	Desulfovibrio alaskensis (strain G20) (Desulfovibrio desulfuricans (strain G20))
Total number of polymer chains	8
Total formula weight	760840.93
Authors	Funk, M.A.,Drennan, C.L. (deposition date: 2018-12-13, release date: 2019-01-16, Last modification date: 2023-10-11)
Primary citation	Orman, M.,Bodea, S.,Funk, M.A.,Campo, A.M.,Bollenbach, M.,Drennan, C.L.,Balskus, E.P. Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. J.Am.Chem.Soc., 141:33-37, 2019 Cited by PubMed: 30557011 DOI: 10.1021/jacs.8b04883 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.364 Å)

Structure validation