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7Z7E
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BU of 7z7e by Molmil
Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4
Descriptor: DARPIN, Isoform 4 of Tumor protein 63, ZINC ION
Authors:Strubel, A, Gebel, J, Chaikuad, A, Muenick, P, Doetsch, V.
Deposit date:2022-03-15
Release date:2022-06-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z71
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BU of 7z71 by Molmil
Crystal structure of p63 DBD in complex with darpin C14
Descriptor: Darpin C14, Isoform 4 of Tumor protein 63, ZINC ION
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z72
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BU of 7z72 by Molmil
Crystal structure of p63 SAM in complex with darpin A5
Descriptor: DI(HYDROXYETHYL)ETHER, Darpin A5, Isoform 9 of Tumor protein 63
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z73
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BU of 7z73 by Molmil
Crystal structure of p63 tetramerization domain in complex with darpin 8F1
Descriptor: Darpin 8F1, Isoform 2 of Tumor protein 63
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z7C
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BU of 7z7c by Molmil
Broadly neutralizing DARPin bnD.8 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BF520)
Descriptor: 1,2-ETHANEDIOL, Broadly neutralizing DARPin bnD.8, Envelope glycoprotein gp160, ...
Authors:Mittl, P.R, Gloegl, M.
Deposit date:2022-03-15
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
7ZYU
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BU of 7zyu by Molmil
HDAC6 ZnF domain inhibitor - DARPin (Designed Ankyrin repeat protein) F10
Descriptor: 1,2-ETHANEDIOL, Designed Ankyrin repeat protein F10, Histone deacetylase 6, ...
Authors:Wang, L, Kempf, G.
Deposit date:2022-05-25
Release date:2022-06-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.
Cell Rep, 39, 2022
8A19
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BU of 8a19 by Molmil
Structure of a leucinostatin derivative determined by host lattice display : L1E4V1 construct
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ...
Authors:Mittl, P.R.E.
Deposit date:2022-06-01
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.358 Å)
Cite:Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Acta Crystallogr D Struct Biol, 78, 2022
8A1A
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BU of 8a1a by Molmil
Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ...
Authors:Mittl, P.R.E.
Deposit date:2022-06-01
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Acta Crystallogr D Struct Biol, 78, 2022
8AIW
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BU of 8aiw by Molmil
Structure of the K5/CagI complex
Descriptor: Cag pathogenicity island protein (Cag19), Designed Ankyrin Repeat Protein K5
Authors:Blanc, M, Guerin, J, Terradot, L.
Deposit date:2022-07-27
Release date:2023-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
Plos Pathog., 19, 2023
8AK1
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BU of 8ak1 by Molmil
Crystal structure of a CagI:K2 complex
Descriptor: Cag pathogenicity island protein (Cag19), Designed Ankyrin Repeat Protein K2
Authors:Blanc, M, Guerin, J, Terradot, L.
Deposit date:2022-07-29
Release date:2023-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
Plos Pathog., 19, 2023
8AED
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BU of 8aed by Molmil
Broadly neutralizing DARPin bnD.9 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BG505)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.9, ...
Authors:Mittl, P, Gloegl, M.
Deposit date:2022-07-13
Release date:2023-08-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
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