8A1A

Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct

Summary for 8A1A

• Entry DOI: 10.2210/pdb8a1a/pdb
• Related: 8A19
• Descriptor: L1F11v1, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, MANGANESE (II) ION, ... (7 entities in total)
• Functional Keywords: host lattice display, leucinostatin, engbf, darpin, de novo protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 149239.58

Authors

Mittl, P.R.E. (deposition date: 2022-06-01, release date: 2022-12-07, Last modification date: 2024-01-31)

• Primary citation: Kiss, C.,Gall, F.M.,Dreier, B.,Adams, M.,Riedl, R.,Pluckthun, A.,Mittl, P.R.E.; Structure of a hydrophobic leucinostatin derivative determined by host lattice display.; Acta Crystallogr D Struct Biol, 78:1439-1450, 2022; PubMed: 36458615; DOI: 10.1107/S2059798322010762

Experimental method

X-RAY DIFFRACTION (2.05 Å)