8AIW

Structure of the K5/CagI complex

Summary for 8AIW

Entry DOI	10.2210/pdb8aiw/pdb
Descriptor	Designed Ankyrin Repeat Protein K5, Cag pathogenicity island protein (Cag19) (3 entities in total)
Functional Keywords	type iv secretion system helicobacter pylori pilus, toxin
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	54666.72
Authors	Blanc, M.,Guerin, J.,Terradot, L. (deposition date: 2022-07-27, release date: 2023-05-17, Last modification date: 2024-02-07)
Primary citation	Blanc, M.,Lettl, C.,Guerin, J.,Vieille, A.,Furler, S.,Briand-Schumacher, S.,Dreier, B.,Berge, C.,Pluckthun, A.,Vadon-Le Goff, S.,Fronzes, R.,Rousselle, P.,Fischer, W.,Terradot, L. Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system. Plos Pathog., 19:e1011368-e1011368, 2023 Cited by PubMed: 37155700 DOI: 10.1371/journal.ppat.1011368 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation