6T3E
| Structure of Thermococcus litoralis Delta(1)-pyrroline-2-carboxylate reductase in complex with NADH and L-proline | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DELTA1-pyrroline-2-carboxylate reductase, PROLINE | 著者 | Ferraris, D.M, Miggiano, R, Ferrario, E, Rizzi, M. | 登録日 | 2019-10-10 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Thermococcus litoralis Delta1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline. Acta Crystallogr D Struct Biol, 76, 2020
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6TVP
| Structure of Mycobacterium smegmatis alpha-maltose-1-phosphate synthase GlgM | 分子名称: | Alpha-maltose-1-phosphate synthase, SODIUM ION | 著者 | Syson, K, Stevenson, C.E.M, Lawson, D.M, Bornemann, S. | 登録日 | 2020-01-10 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the Mycobacterium smegmatis alpha-maltose-1-phosphate synthase GlgM. Acta Crystallogr.,Sect.F, 76, 2020
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6U62
| Raptor-Rag-Ragulator complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Rogala, K.B, Sabatini, D.M. | 登録日 | 2019-08-29 | 公開日 | 2019-10-30 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis for the docking of mTORC1 on the lysosomal surface. Science, 366, 2019
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6ULG
| Cryo-EM structure of the FLCN-FNIP2-Rag-Ragulator complex | 分子名称: | Folliculin, Folliculin-interacting protein 2, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Shen, K, Rogala, K.B, Yu, Z.H, Sabatini, D.M. | 登録日 | 2019-10-08 | 公開日 | 2019-11-20 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex. Cell, 179, 2019
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6UKN
| Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs | 分子名称: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 7, ... | 著者 | Reid, M.S, Kern, D.M, Brohawn, S.G. | 登録日 | 2019-10-05 | 公開日 | 2020-06-10 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. Elife, 9, 2020
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6U6G
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6VH7
| Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue | 分子名称: | Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-09 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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6UVK
| OXA-48 bound by inhibitor CDD-97 | 分子名称: | 1,2-ETHANEDIOL, 1-{4-[4-(2-ethoxyphenyl)piperazin-1-yl]-1,3,5-triazin-2-yl}piperidine-4-carboxylic acid, Beta-lactamase, ... | 著者 | Taylor, D.M, Hu, L, Prasad, B.V.V, Sankaran, B, Palzkill, T.G. | 登録日 | 2019-11-02 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries. Acs Infect Dis., 6, 2020
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6URA
| Crystal structure of RUBISCO from Promineofilum breve | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, Ribulose bisphosphate carboxylase large chain | 著者 | Pereira, J.H, Banda, D.M, Liu, A.K, Shih, P.M, Adams, P.D. | 登録日 | 2019-10-23 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Novel bacterial clade reveals origin of form I Rubisco. Nat.Plants, 6, 2020
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6V1S
| Structure of the Clostridioides difficile transferase toxin | 分子名称: | ADP-ribosylating binary toxin enzymatic subunit CdtA, ADP-ribosyltransferase binding component, CALCIUM ION | 著者 | Sheedlo, M.J, Anderson, D.M, Thomas, A.K, Lacy, D.B. | 登録日 | 2019-11-21 | 公開日 | 2020-03-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme. Proc.Natl.Acad.Sci.USA, 117, 2020
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6V9S
| Structure-based development of subtype-selective orexin 1 receptor antagonists | 分子名称: | CHOLESTEROL, OLEIC ACID, Orexin receptor type 1,GlgA glycogen synthase chimera, ... | 著者 | Hellmann, J, Drabek, M, Yin, J, Huebner, H, Kraus, F, Proell, T, Weikert, D, Kolb, P, Rosenbaum, D.M, Gmeiner, P. | 登録日 | 2019-12-16 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure-based development of a subtype-selective orexin 1 receptor antagonist. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VC9
| TB19 complex | 分子名称: | 1,2-ETHANEDIOL, 5'-nucleotidase, ecto (CD73), ... | 著者 | Zhou, Y.F, Lord, D.M. | 登録日 | 2019-12-20 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms. J.Biol.Chem., 295, 2020
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6VHA
| Singlet Tau Fibril from Corticobasal Degeneration Human Brain Tissue | 分子名称: | Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-09 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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6VHL
| Paired Helical Filament from Alzheimer's Disease Human Brain Tissue | 分子名称: | GLYCINE, Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-10 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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6VCA
| TB38 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, ... | 著者 | Zhou, Y.F, Lord, D.M. | 登録日 | 2019-12-20 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.73 Å) | 主引用文献 | A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms. J.Biol.Chem., 295, 2020
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6VI3
| Straight Filament from Alzheimer's Disease Human Brain Tissue | 分子名称: | GLYCINE, Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-11 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains Cell, 180, 2020
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6W46
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6VMS
| Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane | 分子名称: | Endolysin,D(2) dopamine receptor,D(2) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yin, J, Chen, K.M, Clark, M.J, Hijazi, M, Kumari, P, Bai, X, Sunahara, R.K, Barth, P, Rosenbaum, D.M. | 登録日 | 2020-01-28 | 公開日 | 2020-06-17 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Nature, 584, 2020
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6W47
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2I5J
| Crystal structure of HIV-1 reverse transcriptase (RT) in complex with DHBNH, an RNASE H inhibitor | 分子名称: | (E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE, MAGNESIUM ION, Reverse transcriptase/ribonuclease H P51 subunit, ... | 著者 | Himmel, D.M, Sarafianos, S.G, Knight, J.L, Levy, R.M, Arnold, E. | 登録日 | 2006-08-24 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site. Acs Chem.Biol., 1, 2006
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2J45
| Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Freymann, D.M, Ramirez, U.D. | 登録日 | 2006-08-24 | 公開日 | 2006-11-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Analysis of Protein Hydration in Ultra-High Resolution Structures of the Srp Gtpase Ffh Acta Crystallogr.,Sect.D, 62, 2006
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2J46
| Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Freymann, D.M, Ramirez, U.D. | 登録日 | 2006-08-24 | 公開日 | 2006-11-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Analysis of Protein Hydration in Ultra-High Resolution Structures of the Srp Gtpase Ffh Acta Crystallogr.,Sect.D, 62, 2006
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2O58
| Horse heart met manganese myoglobin | 分子名称: | Myoglobin, PROTOPORPHYRIN IX CONTAINING MN, SULFATE ION | 著者 | Richter-Addo, G.B, Zahran, Z.N, Chooback, L, Copeland, D.M, West, A.H. | 登録日 | 2006-12-05 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations. J.Inorg.Biochem., 102, 2008
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2O5Q
| Manganese horse heart myoglobin, nitric oxide modified | 分子名称: | MANGANESE PROTOPORPHYRIN IX, Myoglobin, NITRIC OXIDE, ... | 著者 | Richter-Addo, G.B, Zahran, Z.N, Chooback, L, Copeland, D.M, West, A.H. | 登録日 | 2006-12-06 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations. J.Inorg.Biochem., 102, 2008
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2O5S
| Cobalt horse heart myoglobin, nitrite modified | 分子名称: | Myoglobin, NITRITE ION, PROTOPORPHYRIN IX CONTAINING CO, ... | 著者 | Richter-Addo, G.B, Zahran, Z.N, Chooback, L, Copeland, D.M, West, A.H. | 登録日 | 2006-12-06 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations. J.Inorg.Biochem., 102, 2008
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