6VMS

Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane

Summary for 6VMS

Entry DOI	10.2210/pdb6vms/pdb
EMDB information	21243
Descriptor	Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	dopamine, dopamine receptor, gpcr, g protein, parkinson's disease, signaling protein
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	5
Total formula weight	166760.00
Authors	Yin, J.,Chen, K.M.,Clark, M.J.,Hijazi, M.,Kumari, P.,Bai, X.,Sunahara, R.K.,Barth, P.,Rosenbaum, D.M. (deposition date: 2020-01-28, release date: 2020-06-17, Last modification date: 2020-08-19)
Primary citation	Yin, J.,Chen, K.M.,Clark, M.J.,Hijazi, M.,Kumari, P.,Bai, X.C.,Sunahara, R.K.,Barth, P.,Rosenbaum, D.M. Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Nature, 584:125-129, 2020 Cited by PubMed: 32528175 DOI: 10.1038/s41586-020-2379-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation