6VHA

Singlet Tau Fibril from Corticobasal Degeneration Human Brain Tissue

Summary for 6VHA

Entry DOI	10.2210/pdb6vha/pdb
EMDB information	21201
Descriptor	Microtubule-associated protein tau (1 entity in total)
Functional Keywords	pathological amyloid fibril, cross-beta fold, parallel beta-sheets, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	34825.13
Authors	Arakhamia, T.,Lee, C.E.,Carlomagno, Y.,Duong, D.M.,Kundinger, S.R.,Wang, K.,Williams, D.,DeTure, M.,Dickson, D.W.,Cook, C.N.,Seyfried, N.T.,Petrucelli, L.,Fitzpatrick, A.W.P. (deposition date: 2020-01-09, release date: 2020-03-04, Last modification date: 2024-03-06)
Primary citation	Arakhamia, T.,Lee, C.E.,Carlomagno, Y.,Duong, D.M.,Kundinger, S.R.,Wang, K.,Williams, D.,DeTure, M.,Dickson, D.W.,Cook, C.N.,Seyfried, N.T.,Petrucelli, L.,Fitzpatrick, A.W.P. Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180:633-644.e12, 2020 Cited by PubMed: 32032505 DOI: 10.1016/j.cell.2020.01.027 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.3 Å)

Structure validation