6VI3

Straight Filament from Alzheimer's Disease Human Brain Tissue

Summary for 6VI3

• Entry DOI: 10.2210/pdb6vi3/pdb
• Related: 6VI3
• EMDB information: 0260
• Descriptor: Microtubule-associated protein tau, GLYCINE (2 entities in total)
• Functional Keywords: pathological amyloid fibril cross-beta fold parallel beta-sheets, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 16891.29

Authors

Arakhamia, T.,Lee, C.E.,Carlomagno, Y.,Duong, D.M.,Kundinger, S.R.,Wang, K.,Williams, D.,DeTure, M.,Dickson, D.W.,Cook, C.N.,Seyfried, N.T.,Petrucelli, L.,Fitzpatrick, A.W.P. (deposition date: 2020-01-11, release date: 2020-04-15, Last modification date: 2024-03-06)

• Primary citation: Arakhamia, T.,Lee, C.E.,Carlomagno, Y.,Duong, D.M.,Kundinger, S.R.,Wang, K.,Williams, D.,DeTure, M.,Dickson, D.W.,Cook, C.N.,Seyfried, N.T.,Petrucelli, L.,Fitzpatrick, A.W.P.; Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains; Cell, 180:633-644.e12, 2020; PubMed: 32032505; DOI: 10.1016/j.cell.2020.01.027

Experimental method

ELECTRON MICROSCOPY (3.3 Å)