6V1S

Structure of the Clostridioides difficile transferase toxin

Summary for 6V1S

Entry DOI	10.2210/pdb6v1s/pdb
EMDB information	21016
Descriptor	ADP-ribosyltransferase binding component, ADP-ribosylating binary toxin enzymatic subunit CdtA, CALCIUM ION (3 entities in total)
Functional Keywords	clostridium, clostridioides, binary, cdt, iota, toxin, translocase
Biological source	Clostridioides difficile More
Total number of polymer chains	8
Total formula weight	746302.22
Authors	Sheedlo, M.J.,Anderson, D.M.,Thomas, A.K.,Lacy, D.B. (deposition date: 2019-11-21, release date: 2020-03-18, Last modification date: 2024-03-06)
Primary citation	Sheedlo, M.J.,Anderson, D.M.,Thomas, A.K.,Lacy, D.B. Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme. Proc.Natl.Acad.Sci.USA, 117:6139-6144, 2020 Cited by PubMed: 32123082 DOI: 10.1073/pnas.1920555117 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation