1F2C
| CRYSTAL STRUCTURE ANALYSIS OF CRYZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (IV) | 分子名称: | 3-[[N-[4-METHYL-PIPERAZINYL]CARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONIC ACID BENZYLOXY-AMIDE, CRUZAIN | 著者 | Brinen, L.S, Hansell, E, Roush, W.R, McKerrow, J.H, Fletterick, R.J. | 登録日 | 2000-05-23 | 公開日 | 2000-07-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease. Structure Fold.Des., 8, 2000
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1F29
| CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO A VINYL SULFONE DERIVED INHIBITOR (I) | 分子名称: | 3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5- PHENYL-PENTANE-1-SULFONYLBENZENE, CRUZAIN | 著者 | Brinen, L.S, Hansell, E, Roush, W.R, McKerrow, J.H, Fletterick, R.J. | 登録日 | 2000-05-23 | 公開日 | 2000-07-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease. Structure Fold.Des., 8, 2000
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1R6H
| Solution Structure of human PRL-3 | 分子名称: | protein tyrosine phosphatase type IVA, member 3 isoform 1 | 著者 | Kozlov, G, Gehring, K, Ekiel, I. | 登録日 | 2003-10-15 | 公開日 | 2004-01-13 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Insights into Molecular Function of the Metastasis-associated Phosphatase PRL-3. J.Biol.Chem., 279, 2004
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5H7N
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5H7Q
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8ID3
| Cryo-EM structure of the 9-hydroxystearic acid bound GPR120-Gi complex | 分子名称: | 9-Hydroxyoctadecanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID8
| Cryo-EM structure of the TUG891 bound GPR120-Gi complex | 分子名称: | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID9
| Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi complex | 分子名称: | 5,8,11,14,17-EICOSAPENTAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID4
| Cryo-EM structure of the linoleic acid bound GPR120-Gi complex | 分子名称: | Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID6
| Cryo-EM structure of the oleic acid bound GPR120-Gi complex | 分子名称: | Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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7WUG
| GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module | 分子名称: | Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ... | 著者 | Qiao, S, Cheng, J.D, Schulman, B.A. | 登録日 | 2022-02-08 | 公開日 | 2022-06-08 | 最終更新日 | 2022-06-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nat Commun, 13, 2022
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6V0Z
| Structure of ALDH7A1 mutant R441C complexed with NAD | 分子名称: | 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Korasick, D.A, Tanner, J.J. | 登録日 | 2019-11-19 | 公開日 | 2020-11-25 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Biochemical, structural, and computational analyses of two new clinically identified missense mutations of ALDH7A1. Chem.Biol.Interact., 2024
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5WUA
| Structure of a Pancreatic ATP-sensitive Potassium Channel | 分子名称: | ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1 | 著者 | Li, N, Wu, J.-X, Chen, L, Gao, N. | 登録日 | 2016-12-16 | 公開日 | 2017-01-25 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structure of a Pancreatic ATP-Sensitive Potassium Channel Cell, 168, 2017
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6EMF
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6EN7
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6EMG
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5ZOF
| Crystal Structure of D181A/R192F hFen1 in complex with DNA | 分子名称: | DNA (5'-D(*AP*CP*TP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*G)-3'), DNA (5'-D(*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*GP*TP*CP*C)-3'), ... | 著者 | Han, W, Hua, Y, Zhao, Y. | 登録日 | 2018-04-13 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | 主引用文献 | Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1. Nucleic Acids Res., 46, 2018
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5ZOE
| Crystal Structure of D181A hFen1 in complex with DNA | 分子名称: | DNA (5'-D(*AP*CP*TP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*G)-3'), DNA (5'-D(*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*GP*TP*CP*C)-3'), ... | 著者 | Han, W, Hua, Y, Zhao, Y. | 登録日 | 2018-04-13 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1. Nucleic Acids Res., 46, 2018
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5ZOD
| Crystal Structure of hFen1 in apo form | 分子名称: | Flap endonuclease 1, MAGNESIUM ION, POTASSIUM ION | 著者 | Han, W, Hua, Y, Zhao, Y. | 登録日 | 2018-04-13 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1. Nucleic Acids Res., 46, 2018
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5ZOG
| Crystal Structure of R192F hFen1 in complex with DNA | 分子名称: | DNA (5'-D(*CP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*GP*AP*T)-3'), DNA (5'-D(P*TP*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), ... | 著者 | Han, W, Hua, Y, Zhao, Y. | 登録日 | 2018-04-13 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1. Nucleic Acids Res., 46, 2018
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8T8L
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8T8K
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7CR6
| Synechocystis Cas1-Cas2/prespacer binary complex | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER) | 著者 | Yu, Y, Chen, Q. | 登録日 | 2020-08-12 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.72 Å) | 主引用文献 | Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis. Nucleic Acids Res., 49, 2021
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7CR8
| Synechocystis Cas1-Cas2-prespacerL complex | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER) | 著者 | Yu, Y, Chen, Q. | 登録日 | 2020-08-12 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis. Nucleic Acids Res., 49, 2021
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8WC3
| Cryo-EM structure of the SEP363856-bound mTAAR1-Gs complex | 分子名称: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | 登録日 | 2023-09-11 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design. Cell, 186, 2023
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