6V0Z

Structure of ALDH7A1 mutant R441C complexed with NAD

Summary for 6V0Z

Entry DOI	10.2210/pdb6v0z/pdb
Descriptor	Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	449899.96
Authors	Korasick, D.A.,Tanner, J.J. (deposition date: 2019-11-19, release date: 2020-11-25, Last modification date: 2024-04-24)
Primary citation	Korasick, D.A.,Buckley, D.P.,Palpacelli, A.,Cursio, I.,Cesaroni, E.,Cheng, J.,Tanner, J.J. Biochemical, structural, and computational analyses of two new clinically identified missense mutations of ALDH7A1. Chem.Biol.Interact., :110993-110993, 2024 Cited by PubMed: 38604394 DOI: 10.1016/j.cbi.2024.110993 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation