6V0Z
Structure of ALDH7A1 mutant R441C complexed with NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Alpha-aminoadipic semialdehyde dehydrogenase | polymer | 513 | 55566.3 | 8 | UniProt (P49419) Pfam (PF00171) In PDB | Homo sapiens (Human) | Alpha-AASA dehydrogenase,Aldehyde dehydrogenase family 7 member A1,Antiquitin-1,Betaine aldehyde dehydrogenase,Delta1-piperideine-6-carboxylate dehydrogenase,P6c dehydrogenase |
| 2 | A, B, C, D, E... | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 3 | C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 1620 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 511 (UniProt: P49419)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Cys 441 | Arg 469 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 444530.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 5369.5 | |
| All* | Total formula weight | 449900.0 |
