8ID8
Cryo-EM structure of the TUG891 bound GPR120-Gi complex
Summary for 8ID8
Entry DOI | 10.2210/pdb8id8/pdb |
EMDB information | 35359 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Free fatty acid receptor 4, ... (6 entities in total) |
Functional Keywords | gpcr, gpr120, complex, fatty acid hormones, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 156822.57 |
Authors | |
Primary citation | Mao, C.,Xiao, P.,Tao, X.N.,Qin, J.,He, Q.T.,Zhang, C.,Guo, S.C.,Du, Y.Q.,Chen, L.N.,Shen, D.D.,Yang, Z.S.,Zhang, H.Q.,Huang, S.M.,He, Y.H.,Cheng, J.,Zhong, Y.N.,Shang, P.,Chen, J.,Zhang, D.L.,Wang, Q.L.,Liu, M.X.,Li, G.Y.,Guo, Y.,Xu, H.E.,Wang, C.,Zhang, C.,Feng, S.,Yu, X.,Zhang, Y.,Sun, J.P. Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380:eadd6220-eadd6220, 2023 Cited by PubMed: 36862765DOI: 10.1126/science.add6220 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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