4N6N
| Crystal structure of oxidized legumain in complex with cystatin E/M | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cystatin-M, IODIDE ION, ... | Authors: | Dall, E, Brandstetter, H. | Deposit date: | 2013-10-14 | Release date: | 2015-02-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain. Angew.Chem.Int.Ed.Engl., 54, 2015
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4N1K
| Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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4N6L
| Crystal structure of human cystatin E/M | Descriptor: | Cystatin-M | Authors: | Dall, E, Brandstetter, H. | Deposit date: | 2013-10-14 | Release date: | 2015-02-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain. Angew.Chem.Int.Ed.Engl., 54, 2015
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4NFF
| Human kallikrein-related peptidase 2 in complex with PPACK | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2 | Authors: | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | Deposit date: | 2013-10-31 | Release date: | 2014-10-29 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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4NFE
| Human kallikrein-related peptidase 2 in complex with benzamidine | Descriptor: | BENZAMIDINE, Kallikrein-2, SULFATE ION | Authors: | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | Deposit date: | 2013-10-31 | Release date: | 2014-10-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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1JH1
| Crystal Structure of MMP-8 complexed with a 6H-1,3,4-thiadiazine derived inhibitor | Descriptor: | BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE, CALCIUM ION, Matrix Metalloproteinase 8, ... | Authors: | Schroder, J, Henke, A, Wenzel, H, Brandstetter, H, Stammler, H.G, Stammler, A, Pfeiffer, W.D, Tschesche, H. | Deposit date: | 2001-06-27 | Release date: | 2001-12-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold. J.Med.Chem., 44, 2001
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1J2Q
| 20S proteasome in complex with calpain-Inhibitor I from archaeoglobus fulgidus | Descriptor: | 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID [1-(1-FORMYL-PENTYLCARBAMOYL)-3-METHYL-BUTYL]-AMIDE, Proteasome alpha subunit, Proteasome beta subunit | Authors: | Groll, M, Brandstetter, H, Bartunik, H, Bourenkow, G, Huber, R. | Deposit date: | 2003-01-08 | Release date: | 2003-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Investigations on the Maturation and Regulation of Archaebacterial Proteasomes J.MOL.BIOL., 327, 2003
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1J2P
| alpha-ring from the proteasome from archaeoglobus fulgidus | Descriptor: | Proteasome alpha subunit | Authors: | Groll, M, Brandstetter, H, Bartunik, H, Bourenkow, G, Huber, R. | Deposit date: | 2003-01-08 | Release date: | 2003-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Investigations on the Maturation and Regulation of Archaebacterial Proteasomes J.MOL.BIOL., 327, 2003
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1ITV
| Dimeric form of the haemopexin domain of MMP9 | Descriptor: | MMP9, SULFATE ION | Authors: | Cha, H, Kopetzki, E, Huber, R, Lanzendoerfer, M, Brandstetter, H. | Deposit date: | 2002-02-11 | Release date: | 2002-09-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of the adaptive molecular recognition by MMP9. J.Mol.Biol., 320, 2002
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1S0P
| Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum. | Descriptor: | Adenylyl cyclase-associated protein, MAGNESIUM ION | Authors: | Ksiazek, D, Brandstetter, H, Israel, L, Bourenkov, G.P, Katchalova, G, Janssen, K.P, Bartunik, H.D, Noegel, A.A, Schleicher, M, Holak, T.A. | Deposit date: | 2004-01-01 | Release date: | 2004-01-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | STRUCTURE OF THE N-TERMINAL DOMAIN OF THE ADENYLYL
CYCLASE-ASSOCIATED PROTEIN (CAP) FROM DICTYOSTELIUM DISCOIDEUM Structure, 11, 2003
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1RFN
| HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | Descriptor: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | Authors: | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | Deposit date: | 1999-04-19 | Release date: | 1999-09-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. Structure Fold.Des., 7, 1999
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4BQD
| KD1 of human TFPI in complex with a synthetic peptide | Descriptor: | GLYCEROL, PEPTIDE, TISSUE FACTOR PATHWAY INHIBITOR (LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR) VARIANT | Authors: | Griessner, A, Brandstetter, H. | Deposit date: | 2013-05-30 | Release date: | 2013-12-04 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor Viia by Tissue Factor Pathway Inhibitor (Tfpi) J.Biol.Chem., 289, 2014
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3ZFP
| Crystal structure of product-like, processed N-terminal protease Npro with internal His-Tag | Descriptor: | CHLORIDE ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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3ZFT
| Crystal structure of product-like, processed N-terminal protease Npro at pH 3 | Descriptor: | CHLORIDE ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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3ZFO
| Crystal structure of substrate-like, unprocessed N-terminal protease Npro mutant S169P | Descriptor: | CHLORIDE ION, HYDROXIDE ION, MONOTHIOGLYCEROL, ... | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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3ZFU
| Crystal structure of substrate-like, unprocessed N-terminal protease Npro mutant S169P with sulphate | Descriptor: | MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO, SULFATE ION | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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3ZFR
| Crystal structure of product-like, processed N-terminal protease Npro with iridium | Descriptor: | HYDROXIDE ION, IRIDIUM (III) ION, MONOTHIOGLYCEROL, ... | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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3ZFQ
| Crystal structure of product-like, processed N-terminal protease Npro with mercury | Descriptor: | MERCURY (II) ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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3ZFN
| Crystal structure of product-like, processed N-terminal protease Npro | Descriptor: | CHLORIDE ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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4A83
| Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in complex with deoxycholate. | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ... | Authors: | Kofler, S, Brandstetter, H. | Deposit date: | 2011-11-18 | Release date: | 2012-05-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1. J.Mol.Biol., 422, 2012
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4A8G
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4ARF
| CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF COLLAGENASE H FROM CLOSTRIDIUM HISTOLYTICUM IN COMPLEX WITH THE PEPTIDIC INHIBITOR ISOAMYLPHOSPHONYL-GLY-PRO-ALA AT 1.77 ANGSTROM RESOLUTION. | Descriptor: | CALCIUM ION, COLH PROTEIN, ISOAMYLPHOSPHONYL-GLY-PRO-ALA, ... | Authors: | Eckhard, U, Brandstetter, H. | Deposit date: | 2012-04-23 | Release date: | 2013-06-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T. J.Biol.Chem., 288, 2013
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4A8V
| Crystal Structure of Birch Pollen Allergen Bet v 1 isoform j in complex with 8-Anilinonaphthalene-1-sulfonate (ANS) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 8-ANILINO-1-NAPHTHALENE SULFONATE, ... | Authors: | Kofler, S, Brandstetter, H. | Deposit date: | 2011-11-21 | Release date: | 2012-05-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1. J.Mol.Biol., 422, 2012
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4A8U
| Crystal Structure of native Birch Pollen Allergen Bet v 1 isoform j | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Kofler, S, Brandstetter, H. | Deposit date: | 2011-11-21 | Release date: | 2012-05-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1. J.Mol.Biol., 422, 2012
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1MT3
| Crystal Structure of the Tricorn Interacting Factor Selenomethionine-F1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proline iminopeptidase | Authors: | Goettig, P, Groll, M, Kim, J.-S, Huber, R, Brandstetter, H. | Deposit date: | 2002-09-20 | Release date: | 2002-11-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism Embo J., 21, 2002
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