4N6L

Crystal structure of human cystatin E/M

Summary for 4N6L

Entry DOI	10.2210/pdb4n6l/pdb
Related	4N6M 4N6N 4N6O
Descriptor	Cystatin-M (2 entities in total)
Functional Keywords	cysteine protease inhibitor, legumain, asparaginyl endopeptidase, reactive center loop, papain, cathepsin, cancer, cystatin fold, protease inhibitor, hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Secreted: Q15828
Total number of polymer chains	1
Total formula weight	14924.93
Authors	Dall, E.,Brandstetter, H. (deposition date: 2013-10-14, release date: 2015-02-18, Last modification date: 2023-09-20)
Primary citation	Dall, E.,Fegg, J.C.,Briza, P.,Brandstetter, H. Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain. Angew.Chem.Int.Ed.Engl., 54:2917-2921, 2015 Cited by PubMed: 25630877 DOI: 10.1002/anie.201409135 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.952 Å)

Structure validation