4N6N
Crystal structure of oxidized legumain in complex with cystatin E/M
Summary for 4N6N
Entry DOI | 10.2210/pdb4n6n/pdb |
Related | 4N6L 4N6M 4N6O |
Descriptor | Legumain, Cystatin-M, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | complex, cysteine protease, inhibitor, legumain, asparaginyl endopeptidase, reactive center loop, papain, cathepsin, cancer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 48260.03 |
Authors | Dall, E.,Brandstetter, H. (deposition date: 2013-10-14, release date: 2015-02-18, Last modification date: 2023-11-15) |
Primary citation | Dall, E.,Fegg, J.C.,Briza, P.,Brandstetter, H. Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain. Angew.Chem.Int.Ed.Engl., 54:2917-2921, 2015 Cited by PubMed: 25630877DOI: 10.1002/anie.201409135 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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