4BQD

KD1 of human TFPI in complex with a synthetic peptide

Summary for 4BQD

Entry DOI	10.2210/pdb4bqd/pdb
Descriptor	TISSUE FACTOR PATHWAY INHIBITOR (LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR) VARIANT, PEPTIDE, GLYCEROL, ... (4 entities in total)
Functional Keywords	blood clotting
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	4
Total formula weight	23468.56
Authors	Griessner, A.,Brandstetter, H. (deposition date: 2013-05-30, release date: 2013-12-04, Last modification date: 2019-07-17)
Primary citation	Dockal, M.,Hartman, R.,Fries, M.,Christella, M.,Thomassen, L.G.D.,Heizman, A.,Ehrlich, H.,Rosing, J.,Osterkamp, F.,Polakowski, T.,Reineke, U.,Griessner, A.,Brandstetter, H.,Scheiflinger, F. Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor Viia by Tissue Factor Pathway Inhibitor (Tfpi) J.Biol.Chem., 289:1732-, 2014 Cited by PubMed: 24275667 DOI: 10.1074/JBC.M113.533836 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation