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4F2J
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BU of 4f2j by Molmil
Crystal structure of ZNF217 bound to DNA, P6522 crystal form
Descriptor: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', ZINC ION, Zinc finger protein 217
Authors:Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P.
Deposit date:2012-05-08
Release date:2013-02-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217
J.Biol.Chem., 288, 2013
4X5S
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BU of 4x5s by Molmil
The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase (Carbonate dehydratase), ...
Authors:De Simone, G, Alterio, V, Di Fiore, A.
Deposit date:2014-12-05
Release date:2015-05-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense.
Bioorg.Med.Chem.Lett., 25, 2015
6OKO
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BU of 6oko by Molmil
Crystal structure of mRIPK3 complexed with N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
Descriptor: 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3
Authors:Pokross, M.E.
Deposit date:2019-04-14
Release date:2019-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.
Acs Med.Chem.Lett., 11, 2020
5KW1
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BU of 5kw1 by Molmil
Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue
Descriptor: CHLORIDE ION, DNA/RNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KVY
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BU of 5kvy by Molmil
CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG
Descriptor: CHLORIDE ION, DNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Hsiao, H.-H, Crichlow, G.V, Albright, R.A, Murphy, J.W, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
3IJJ
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BU of 3ijj by Molmil
Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer)
Descriptor: (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid, (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ...
Authors:Crichlow, G.V, Cho, Y, Lolis, E.J.
Deposit date:2009-08-04
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IJG
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BU of 3ijg by Molmil
Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013
Descriptor: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor
Authors:Crichlow, G.V, Cho, Y, Lolis, E.J.
Deposit date:2009-08-04
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
3P90
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BU of 3p90 by Molmil
Crystal Structure Analysis of H207F Mutant of Human CLIC1
Descriptor: Chloride intracellular channel protein 1
Authors:Cross, M.O, Fanucchi, S, Achilonu, I.A, Fernandes, M.A, Dirr, H.W.
Deposit date:2010-10-15
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of individual histidines in the pH-dependent global stability of human chloride intracellular channel 1.
Biochemistry, 51, 2012
5LLQ
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BU of 5llq by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119F variant
Descriptor: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2016-07-28
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.
Biochim.Biophys.Acta, 1861, 2016
1GOW
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BU of 1gow by Molmil
BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS
Descriptor: BETA-GLYCOSIDASE
Authors:Pearl, L.H, Aguilar, C.F, Sanderson, I.
Deposit date:1996-09-19
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: resilience as a key factor in thermostability.
J.Mol.Biol., 271, 1997
4ZYE
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BU of 4zye by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase
Descriptor: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase, NITRATE ION
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
5LBH
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BU of 5lbh by Molmil
Crystal structure of Helicobacter cinaedi CAIP
Descriptor: CAIP, FE (III) ION
Authors:Zanotti, G, Valesse, F, Codolo, G, De Bernard, M.
Deposit date:2016-06-16
Release date:2017-04-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells.
Sci Rep, 7, 2017
4ZYG
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BU of 4zyg by Molmil
Crystal structure of methylated Sulfolobus solfataricus O6-methylguanine methyltransferase
Descriptor: Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYH
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BU of 4zyh by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119L variant
Descriptor: Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4YF5
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BU of 4yf5 by Molmil
Crystal structure of Rv1284 in the presence of polycarpine at acidic pH
Descriptor: Beta-carbonic anhydrase 1, CHLORIDE ION, ZINC ION
Authors:Hofmann, A.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
Febs J., 282, 2015
4YF6
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BU of 4yf6 by Molmil
Crystal structure of oxidised Rv1284
Descriptor: Beta-carbonic anhydrase 1, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hofmann, A.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
Febs J., 282, 2015
4YF4
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BU of 4yf4 by Molmil
Crystal structure of Rv1284 in the presence of polycarpine at mildly acidic pH
Descriptor: Beta-carbonic anhydrase 1, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hofmann, A.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
Febs J., 282, 2015
4ZYD
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BU of 4zyd by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.682 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
5KC6
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BU of 5kc6 by Molmil
Crystal structure of Cbln1 (Val55-Gly58 deletion mutant)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1
Authors:Elegheert, J, Clay, J.E, Aricescu, A.R.
Deposit date:2016-06-05
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for integration of GluD receptors within synaptic organizer complexes.
Science, 353, 2016
5H0U
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BU of 5h0u by Molmil
Crystal structure of the catalytic domain of membrane type 1 matrix metalloproteinase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Ogata, H, Decaneto, E, Lubitz, W.
Deposit date:2016-10-07
Release date:2017-10-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.239 Å)
Cite:Solvent water interactions within the active site of the membrane type I matrix metalloproteinase.
Phys Chem Chem Phys, 19, 2017
7P4G
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BU of 7p4g by Molmil
Rabbit Muscle L-lactate dehydrogenase in complex with citrate
Descriptor: CITRIC ACID, L-lactate dehydrogenase A chain
Authors:Iacovino, L.G, Binda, C, Hochkoeppler, A.
Deposit date:2021-07-11
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme.
Biochimie, 199, 2022
1NSW
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BU of 1nsw by Molmil
The Crystal Structure of the K18G Mutant of the thioredoxin from Alicyclobacillus acidocaldarius
Descriptor: THIOREDOXIN
Authors:Bartolucci, S, De Simone, G, Galdiero, S, Improta, R, Menchise, V, Pedone, C, Pedone, E, Saviano, M.
Deposit date:2003-01-28
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
J.Bacteriol., 185, 2003
1NW2
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BU of 1nw2 by Molmil
The crystal structure of the mutant R82E of Thioredoxin from Alicyclobacillus acidocaldarius
Descriptor: ACETATE ION, CACODYLATE ION, THIOREDOXIN, ...
Authors:Bartolucci, S, De Simone, G, Galdiero, S, Improta, R, Menchise, V, Pedone, C, Pedone, E, Saviano, M.
Deposit date:2003-02-05
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
J.Bacteriol., 185, 2003
4ALO
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BU of 4alo by Molmil
STRUCTURE AND PROPERTIES OF H1 CRUSTACYANIN FROM LOBSTER HOMARUS AMERICANUS
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, H1 APOCRUSTACYANIN, SODIUM ION, ...
Authors:Ferrari, M, Folli, C, Pincolini, E, Mcclintock, T.S, Roessle, M, Berni, R, Cianci, M.
Deposit date:2012-03-05
Release date:2012-08-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural Characterization of Recombinant Crustacyanin Subunits from the Lobster Homarus Americanus.
Acta Crystallogr.,Sect.F, 68, 2012
3LG8
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BU of 3lg8 by Molmil
Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase
Descriptor: A-type ATP synthase subunit E
Authors:Balakrishna, A.M, Manimekalai, M.S.S, Hunke, C, Gayen, S, Jeyakanthan, J, Gruber, G.
Deposit date:2010-01-19
Release date:2010-07-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering
J.Bioenerg.Biomembr., 42, 2010

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