5H0U

Crystal structure of the catalytic domain of membrane type 1 matrix metalloproteinase

Summary for 5H0U

• Entry DOI: 10.2210/pdb5h0u/pdb
• Descriptor: Matrix metalloproteinase-14, HIS-HIS-HIS-HIS-HIS-HIS, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: catalytic domain membrane type 1 matrix metalloproteinase mt1-mmp, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane ; Single-pass type I membrane protein : P50281
• Total number of polymer chains: 2
• Total formula weight: 21436.66

Authors

Ogata, H.,Decaneto, E.,Lubitz, W. (deposition date: 2016-10-07, release date: 2017-10-04, Last modification date: 2024-01-10)

• Primary citation: Decaneto, E.,Vasilevskaya, T.,Kutin, Y.,Ogata, H.,Grossman, M.,Sagi, I.,Havenith, M.,Lubitz, W.,Thiel, W.,Cox, N.; Solvent water interactions within the active site of the membrane type I matrix metalloproteinase.; Phys Chem Chem Phys, 19:30316-30331, 2017; PubMed: 28951896; DOI: 10.1039/c7cp05572b

Experimental method

X-RAY DIFFRACTION (2.239 Å)