4ZYD
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
Summary for 4ZYD
Entry DOI | 10.2210/pdb4zyd/pdb |
Descriptor | Methylated-DNA--protein-cysteine methyltransferase, DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), ... (4 entities in total) |
Functional Keywords | transferase, extremophiles, dna repair, alkylated dna-protein alkyltransferase, protein-dna complex, cell cycle |
Biological source | Sulfolobus solfataricus More |
Cellular location | Cytoplasm : Q97VW7 |
Total number of polymer chains | 3 |
Total formula weight | 24985.22 |
Authors | Miggiano, R.,Rossi, F.,Rizzi, M. (deposition date: 2015-05-21, release date: 2015-08-12, Last modification date: 2024-01-10) |
Primary citation | Perugino, G.,Miggiano, R.,Serpe, M.,Vettone, A.,Valenti, A.,Lahiri, S.,Rossi, F.,Rossi, M.,Rizzi, M.,Ciaramella, M. Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein. Nucleic Acids Res., 43:8801-8816, 2015 Cited by PubMed: 26227971DOI: 10.1093/nar/gkv774 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.682 Å) |
Structure validation
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