4ZYD
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Methylated-DNA--protein-cysteine methyltransferase | polymer | 151 | 17028.0 | 1 | UniProt (Q97VW7) Pfam (PF01035) In PDB | Sulfolobus solfataricus | 6-O-methylguanine-DNA methyltransferase,MGMT,O-6-methylguanine-DNA-alkyltransferase |
| 2 | B | DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3') | polymer | 13 | 4005.6 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3') | polymer | 13 | 3951.6 | 1 | synthetic construct | ||
| 4 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A: 1 - 151 (UniProt: Q97VW7)
| PDB | External Database | Details |
|---|---|---|
| Ala 119 | Cys 119 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 24985.2 | |
| All* | Total formula weight | 24985.2 |
