Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119L variant

Summary for 4ZYH

DescriptorMethylated-DNA--protein-cysteine methyltransferase (2 entities in total)
Functional Keywordsextremophiles, dna repair, alkylated dna-protein alkyltransferase, transferase
Biological sourceSulfolobus solfataricus
Cellular locationCytoplasm  Q97VW7
Total number of polymer chains1
Total molecular weight17070.08
Miggiano, R.,Rossi, F.,Rizzi, M. (deposition date: 2015-05-21, release date: 2015-08-12, Last modification date: 2015-10-28)
Primary citation
Perugino, G.,Miggiano, R.,Serpe, M.,Vettone, A.,Valenti, A.,Lahiri, S.,Rossi, F.,Rossi, M.,Rizzi, M.,Ciaramella, M.
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43:8801-8816, 2015
PubMed: 26227971 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkv774
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24380.7%1.6%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload