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5KVY

CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG

Summary for 5KVY
Entry DOI10.2210/pdb5kvy/pdb
Related5KW1 5KW6
DescriptorPoly(U)-binding-splicing factor PUF60, DNA (30-MER), CHLORIDE ION, ... (4 entities in total)
Functional Keywordstandem rrms, protein-nucleic acid complex, splicing factor, splicing-dna complex, splicing/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight55714.95
Authors
Hsiao, H.-H.,Crichlow, G.V.,Albright, R.A.,Murphy, J.W.,Lolis, E.J.,Braddock, D.T. (deposition date: 2016-07-15, release date: 2017-08-23, Last modification date: 2023-10-04)
Primary citationHsiao, H.T.,Crichlow, G.V.,Murphy, J.W.,Folta-Stogniew, E.J.,Lolis, E.J.,Braddock, D.T.
Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15:e0242725-e0242725, 2020
Cited by
PubMed: 33253191
DOI: 10.1371/journal.pone.0242725
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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