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7M1P
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BU of 7m1p by Molmil
Human ABCA4 structure in the unbound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
Authors:Scortecci, J.F, Van Petegem, F, Molday, R.S.
Deposit date:2021-03-14
Release date:2021-09-08
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease.
Nat Commun, 12, 2021
7KR6
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BU of 7kr6 by Molmil
Glycoside hydrolase family 16 endo-glucanase from Bacteroides ovatus in complex with G4G3G-2F-DNP
Descriptor: Glycoside hydrolase family 16 protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-2-deoxy-2-fluoro-alpha-D-glucopyranose
Authors:Tamura, K, Brumer, H, van Petegem, F.
Deposit date:2020-11-18
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Orthogonal Active-Site Labels for Mixed-Linkage endo-beta-Glucanases.
Acs Chem.Biol., 16, 2021
6B27
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BU of 6b27 by Molmil
Crystal structure of human STAC2 Tandem SH3 Domains (296-411) in complex with a CaV1.1 II-III loop peptide
Descriptor: CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 2, SULFATE ION, ...
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B28
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BU of 6b28 by Molmil
Crystal structure of human STAC2 Tandem SH3 Domains Q347I (296-411)
Descriptor: SH3 and cysteine-rich domain-containing protein 2
Authors:Wong King Yuen, S.M, Tung, C.C, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B26
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BU of 6b26 by Molmil
Crystal structure of human STAC2 Tandem SH3 Domains (296-411)
Descriptor: SH3 and cysteine-rich domain-containing protein 2
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B25
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BU of 6b25 by Molmil
Crystal structure of human STAC1 Tandem SH3 Domains (288-402)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B29
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BU of 6b29 by Molmil
Crystal structure of the second SH3 domain of STAC3 (309-364)
Descriptor: SH3 and cysteine-rich domain-containing protein 3
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DAF
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BU of 6daf by Molmil
2.4 Angstrom crystal structure of the F141L Ca/CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAE
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BU of 6dae by Molmil
2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Lu, J, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAD
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BU of 6dad by Molmil
1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAH
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BU of 6dah by Molmil
2.5 Angstrom crystal structure of the N97S CaM mutant
Descriptor: CALCIUM ION, Calmodulin-1
Authors:Wang, K, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5SV8
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BU of 5sv8 by Molmil
Crystal Structure of the catalytic nucleophile and surface cysteine mutant of VvEG16 in complex with a xyloglucan oligosaccharide
Descriptor: alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, probable xyloglucan endotransglucosylase/hydrolase protein 19
Authors:McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
Deposit date:2016-08-05
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.588 Å)
Cite:Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
5VSN
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BU of 5vsn by Molmil
Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L
Descriptor: GLYCEROL, POTASSIUM ION, Ryanodine receptor 2
Authors:Yuchi, Z, Van Petegem, F.
Deposit date:2017-05-12
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.439 Å)
Cite:Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2.
JCI Insight, 5, 2019
3QR5
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BU of 3qr5 by Molmil
Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted
Descriptor: Cardiac Ca2+ release channel
Authors:Lobo, P.A, Van Petegem, F.
Deposit date:2011-02-17
Release date:2011-06-08
Last modified:2023-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The deletion of exon 3 in the cardiac ryanodine receptor is rescued by beta strand switching.
Structure, 19, 2011
4MZ2
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BU of 4mz2 by Molmil
Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain
Descriptor: Sodium channel subunit beta-4
Authors:Das, S, Van Petegem, F.
Deposit date:2013-09-28
Release date:2013-12-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.722 Å)
Cite:Crystallographic insights into sodium-channel modulation by the beta 4 subunit.
Proc.Natl.Acad.Sci.USA, 110, 2013
4MZ3
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BU of 4mz3 by Molmil
Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant
Descriptor: Sodium channel subunit beta-4
Authors:Das, S, Van Petegem, F.
Deposit date:2013-09-28
Release date:2013-12-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.741 Å)
Cite:Crystallographic insights into sodium-channel modulation by the beta 4 subunit.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ILA
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BU of 3ila by Molmil
Crystal structure of rabbit ryanodine receptor 1 N-terminal domain (9-205)
Descriptor: Ryanodine receptor 1
Authors:Lobo, P.A, Van Petegem, F.
Deposit date:2009-08-06
Release date:2009-11-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations.
Structure, 17, 2009
4P9I
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BU of 4p9i by Molmil
Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253)
Descriptor: Ryanodine receptor 2
Authors:Lau, K, Van Petegem, F.
Deposit date:2014-04-04
Release date:2014-11-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.3401 Å)
Cite:Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
3DVE
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BU of 3dve by Molmil
Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin, NICKEL (II) ION, ...
Authors:Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
Deposit date:2008-07-18
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVM
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BU of 3dvm by Molmil
Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A
Authors:Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
Deposit date:2008-07-18
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVK
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BU of 3dvk by Molmil
Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin, Voltage-dependent R-type calcium channel subunit alpha-1E
Authors:Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
Deposit date:2008-07-18
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3FYQ
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BU of 3fyq by Molmil
Structure of Drosophila melanogaster talin IBS2 domain (residues 1981-2168)
Descriptor: CG6831-PA (Talin)
Authors:Cheung, T.Y.S, Fairchild, M.J, Zarivach, R, Tanentzapf, G, Van Petegem, F.
Deposit date:2009-01-22
Release date:2009-02-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the talin integrin binding domain 2.
J.Mol.Biol., 387, 2009
3DVJ
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BU of 3dvj by Molmil
Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex
Descriptor: CALCIUM ION, Calmodulin, Voltage-dependent N-type calcium channel subunit alpha-1B
Authors:Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
Deposit date:2008-07-18
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
4I8M
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BU of 4i8m by Molmil
Crystal structure of rabbit Ryanodine receptor 1 (residues 1-536) disease mutant V219I
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-12-03
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
4I1E
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BU of 4i1e by Molmil
Crystal structure of Rabbit Ryanodine Receptor 1 (residues 1-536) disease mutant G249R
Descriptor: Ryanodine receptor 1
Authors:Kimlicka, L, Van Petegem, F.
Deposit date:2012-11-20
Release date:2013-02-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013

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