4I1E
Crystal structure of Rabbit Ryanodine Receptor 1 (residues 1-536) disease mutant G249R
Summary for 4I1E
| Entry DOI | 10.2210/pdb4i1e/pdb |
| Related | 2XOA 4I0Y 4I2S 4I37 4I3N 4I6I 4I7I 4I8M 4I96 |
| Descriptor | Ryanodine receptor 1 (2 entities in total) |
| Functional Keywords | calcium channel, er/sr membrane, metal transport |
| Biological source | Oryctolagus cuniculus (rabbit) |
| Cellular location | Sarcoplasmic reticulum membrane; Multi-pass membrane protein: P11716 |
| Total number of polymer chains | 1 |
| Total formula weight | 59576.52 |
| Authors | Kimlicka, L.,Van Petegem, F. (deposition date: 2012-11-20, release date: 2013-02-20, Last modification date: 2024-02-28) |
| Primary citation | Kimlicka, L.,Lau, K.,Tung, C.C.,Van Petegem, F. Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface. Nat Commun, 4:1506-1506, 2013 Cited by PubMed: 23422674DOI: 10.1038/ncomms2501 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report
