5VSN
Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L
Summary for 5VSN
Entry DOI | 10.2210/pdb5vsn/pdb |
Descriptor | Ryanodine receptor 2, GLYCEROL, POTASSIUM ION, ... (4 entities in total) |
Functional Keywords | ryanodine receptor, disease mutant, transport protein |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 19295.73 |
Authors | Yuchi, Z.,Van Petegem, F. (deposition date: 2017-05-12, release date: 2018-05-23, Last modification date: 2023-10-04) |
Primary citation | Alvarado, F.J.,Bos, J.M.,Yuchi, Z.,Valdivia, C.R.,Hernandez, J.J.,Zhao, Y.T.,Henderlong, D.S.,Chen, Y.,Booher, T.R.,Marcou, C.A.,Van Petegem, F.,Ackerman, M.J.,Valdivia, H.H. Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2. JCI Insight, 5:-, 2019 Cited by PubMed: 30835254DOI: 10.1172/jci.insight.126544 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.439 Å) |
Structure validation
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