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5VSN

Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L

Summary for 5VSN
Entry DOI10.2210/pdb5vsn/pdb
DescriptorRyanodine receptor 2, GLYCEROL, POTASSIUM ION, ... (4 entities in total)
Functional Keywordsryanodine receptor, disease mutant, transport protein
Biological sourceMus musculus (Mouse)
Total number of polymer chains1
Total formula weight19295.73
Authors
Yuchi, Z.,Van Petegem, F. (deposition date: 2017-05-12, release date: 2018-05-23, Last modification date: 2023-10-04)
Primary citationAlvarado, F.J.,Bos, J.M.,Yuchi, Z.,Valdivia, C.R.,Hernandez, J.J.,Zhao, Y.T.,Henderlong, D.S.,Chen, Y.,Booher, T.R.,Marcou, C.A.,Van Petegem, F.,Ackerman, M.J.,Valdivia, H.H.
Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2.
JCI Insight, 5:-, 2019
Cited by
PubMed: 30835254
DOI: 10.1172/jci.insight.126544
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.439 Å)
Structure validation

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