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5VSN

Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ryanodine receptor 2polymer16919164.51UniProt (E9Q401)
Pfam (PF00622)
Mus musculus (Mouse)RyR2, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, Type 2 ryanodine receptor
2B
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3C
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
4D
(A)
waterwater18.0111Chemie (HOH)
Sequence modifications
A: 1084 - 1252 (UniProt: E9Q401)
PDBExternal DatabaseDetails
Leu 1124Pro 1124engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19164.5
Non-Polymers*Number of molecules2
Total formula weight131.2
All*Total formula weight19295.7
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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