7PB2
| Crystal structure of JDI TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK) | Descriptor: | Beta-2-microglobulin, KRAS G12D peptide (VVVGADGVGK), MHC class I antigen, ... | Authors: | Coles, C.H, Karuppiah, V, Robinson, R.A. | Deposit date: | 2021-07-30 | Release date: | 2022-07-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen Nat Commun, 13, 2022
|
|
7OW3
| |
7OW5
| |
7OW6
| |
7Q9A
| MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR | Descriptor: | Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
|
|
7Q98
| MHC Class I A02 Allele presenting NLSALGIFST | Descriptor: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | Authors: | Rizkallah, P.J, Sewell, A.K. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
|
|
7Q99
| MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR | Descriptor: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
|
|
7Q9B
| MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
|
|
6QPM
| Adenovirus serotype 10 Fiber-Knob | Descriptor: | Fiber protein | Authors: | Baker, A.T, Rizkallah, P.J. | Deposit date: | 2019-02-14 | Release date: | 2020-08-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Development of a low-seroprevalence, alpha v beta 6 integrin-selective virotherapy based on human adenovirus type 10. Mol Ther Oncolytics, 25, 2022
|
|
3H7B
| |
3H9H
| |
3IXA
| |
6Z9V
| Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | Deposit date: | 2020-06-04 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol., 207, 2021
|
|
6Z9W
| Human Class I Major Histocompatibility Complex, A02 allele, presenting LLGWVFAQV | Descriptor: | Beta-2-microglobulin, LEU-LEU-GLY-TRP-VAL-PHE-ALA-GLN-VAL, MHC class I antigen | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | Deposit date: | 2020-06-04 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol., 207, 2021
|
|
6Z9X
| Human Class I Major Histocompatibility Complex, A02 allele, presenting LLS (t-butyl)Y FGTPT | Descriptor: | Beta-2-microglobulin, LEU-LEU-SER-TUR-PHE-GLY-THR-PRO-THR, MHC class I antigen, ... | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | Deposit date: | 2020-06-04 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol., 207, 2021
|
|
6ZC5
| Human Adenovirus serotype D10 FiberKnob protein | Descriptor: | Fiber | Authors: | Baker, A.T, Mundy, R.M, Rizkallah, P.J, Parker, A.L. | Deposit date: | 2020-06-09 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Development of a low-seroprevalence, alpha v beta 6 integrin-selective virotherapy based on human adenovirus type 10. Mol Ther Oncolytics, 25, 2022
|
|
6ZKX
| Crystal structure of InhA:01 TCR in complex with HLA-E (Y84C) bound to InhA (53-61 GCG) | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | Authors: | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | Deposit date: | 2020-06-30 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
|
|
6ZKY
| Crystal structure of InhA:01 TCR in complex with HLA-E (S147C) bound to InhA (53-61 H3C) | Descriptor: | Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ... | Authors: | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | Deposit date: | 2020-06-30 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
|
|
6ZKZ
| Crystal structure of InhA:01 TCR in complex with HLA-E (F116C) bound to InhA (53-61 H4C) | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | Authors: | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | Deposit date: | 2020-06-30 | Release date: | 2022-01-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
|
|
6ZKW
| Crystal structure of InhA:01 TCR in complex with HLA-E bound to InhA (53-61) | Descriptor: | Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ... | Authors: | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | Deposit date: | 2020-06-30 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
|
|
7ZT8
| Structure of E8 TCR in complex in human MR1 bound to 3FBA | Descriptor: | 1,2-ETHANEDIOL, 3-methylbenzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
|
|
7ZT3
| Structure of E8 TCR in complex in human MR1 K43A | Descriptor: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ... | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
|
|
7ZT2
| Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU | Descriptor: | 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ... | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
|
|
7ZT4
| Structure of E8 TCR in complex with human MR1 bound to 6FP | Descriptor: | 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | Authors: | Karuppiah, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
|
|
7ZT5
| Structure of E8 TCR in complex in human MR1 bound to 3FSA | Descriptor: | 3-methanoyl-2-oxidanyl-benzoic acid, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | Authors: | Karuppiah, V, Robinson, R.A. | Deposit date: | 2022-05-09 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. J.Exp.Med., 220, 2023
|
|