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5JN9
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BU of 5jn9 by Molmil
Crystal structure for the complex of human carbonic anhydrase IV and ethoxyzolamide
Descriptor: 6-ethoxy-1,3-benzothiazole-2-sulfonamide, ACETATE ION, Carbonic anhydrase 4, ...
Authors:Chen, Z, Waheed, A, Di Cera, E, Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
5JNA
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BU of 5jna by Molmil
Crystal structure for the complex of human carbonic anhydrase IV and topiramate
Descriptor: ACETATE ION, Carbonic anhydrase 4, GLYCEROL, ...
Authors:Chen, Z, Waheed, A, Di Cera, E, Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
4AKQ
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BU of 4akq by Molmil
Mutations in the neighbourhood of CotA-laccase trinuclear site: E498D mutant
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ...
Authors:Silva, C.S, Chen, Z, Durao, P, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I.
Deposit date:2012-02-28
Release date:2012-03-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Role of Glu498 in the Dioxygen Reactivity of Cota-Laccase from Bacillus Subtilis.
Dalton Trans, 39, 2010
5JXT
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BU of 5jxt by Molmil
Crystal structure of MtISWI bound with histone H4 tail
Descriptor: Chromatin-remodeling complex ATPase-like protein, Histone H4
Authors:Chen, Z, Yan, L.
Deposit date:2016-05-13
Release date:2016-12-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Structure and regulation of the chromatin remodeller ISWI
Nature, 540, 2016
4AKP
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BU of 4akp by Molmil
Mutations in the neighbourhood of CotA-laccase trinuclear site: E498T mutant
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ...
Authors:Silva, C.S, Chen, Z, Durao, P, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I.
Deposit date:2012-02-28
Release date:2012-03-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Role of Glu498 in the Dioxygen Reactivity of Cota-Laccase from Bacillus Subtilis.
Dalton Trans, 39, 2010
4AKO
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BU of 4ako by Molmil
Mutations in the neighbourhood of CotA-laccase trinuclear site: E498L mutant
Descriptor: 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ...
Authors:Silva, C.S, Chen, Z, Durao, P, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I.
Deposit date:2012-02-28
Release date:2012-03-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Role of Glu498 in the Dioxygen Reactivity of Cota-Laccase from Bacillus Subtilis.
Dalton Trans, 39, 2010
2P5B
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BU of 2p5b by Molmil
The complex structure of JMJD2A and trimethylated H3K36 peptide
Descriptor: FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ...
Authors:Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y.
Deposit date:2007-03-14
Release date:2007-06-12
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
8SYN
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BU of 8syn by Molmil
Human VPS35L/VPS29/VPS26C Complex
Descriptor: VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 26C, Vacuolar protein sorting-associated protein 29
Authors:Chen, Z, Chen, B, Burstein, E, Han, Y.
Deposit date:2023-05-25
Release date:2023-11-01
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural organization of the retriever-CCC endosomal recycling complex.
Nat.Struct.Mol.Biol., 31, 2024
8SYM
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BU of 8sym by Molmil
Human VPS29/VPS35L Complex (Locally refined map)
Descriptor: VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 29
Authors:Chen, Z, Chen, B, Burstein, E, Han, Y.
Deposit date:2023-05-25
Release date:2023-11-01
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural organization of the retriever-CCC endosomal recycling complex.
Nat.Struct.Mol.Biol., 31, 2024
8SYO
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BU of 8syo by Molmil
Human Retriever VPS35L/VPS29/VPS26C Complex (Composite Map)
Descriptor: VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 26C, Vacuolar protein sorting-associated protein 29
Authors:Chen, Z, Chen, B, Burstein, E, Han, Y.
Deposit date:2023-05-25
Release date:2023-11-01
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural organization of the retriever-CCC endosomal recycling complex.
Nat.Struct.Mol.Biol., 31, 2024
6BB3
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BU of 6bb3 by Molmil
Lactate Dehydrogenase in complex with inhibitor 3-((2-chlorophenyl)thio)-6-(6-((4-fluorophenyl)amino)pyridin-2-yl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one
Descriptor: (6R)-3-[(2-chlorophenyl)sulfanyl]-6-{6-[(4-fluorophenyl)amino]pyridin-2-yl}-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Chen, Z, Eigenbrot, C.
Deposit date:2017-10-16
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase
To Be Published
3CX6
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BU of 3cx6 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein alpha-13 subunit, MAGNESIUM ION, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
3CX7
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BU of 3cx7 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP-AlF4
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Glutamate Transporter Associated Protein 48, Guanine Nucleotide-Binding Protein Galpha 13, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
3SGZ
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BU of 3sgz by Molmil
High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole.
Descriptor: 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 2
Authors:Chen, Z, Vignaud, C, Jaafar, A, Gueritte, F, Guenard, D, Lederer, F, Mathews, F.S.
Deposit date:2011-06-15
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.
Biochimie, 94, 2012
5X3E
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BU of 5x3e by Molmil
kinesin 6
Descriptor: IODIDE ION, Kinesin-like protein, SULFATE ION
Authors:Chen, Z, Guan, R, Zhang, L.
Deposit date:2017-02-04
Release date:2017-04-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin
Nat Commun, 8, 2017
6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6BCA
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BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
5ZBN
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BU of 5zbn by Molmil
Structure of glycolate oxidase without FMN from Nicotiana benthamiana
Descriptor: Glycolate oxidase, PHOSPHATE ION
Authors:Chen, Z, Liu, Y.
Deposit date:2018-02-12
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structures of glycolate oxidase from Nicotiana benthamiana reveal a conserved pH sensor affecting the binding of FMN.
Biochem.Biophys.Res.Commun., 503, 2018
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
3UTM
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BU of 3utm by Molmil
Crystal structure of a mouse Tankyrase-Axin complex
Descriptor: Axin-1, Tankyrase-1
Authors:Cheng, Z, Morrone, S, Xu, W.
Deposit date:2011-11-26
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
5WUK
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BU of 5wuk by Molmil
Crystal structure of EED [G255D] in complex with EZH2 peptide and EED226 compound
Descriptor: GLYCEROL, Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ...
Authors:Chen, Z.
Deposit date:2016-12-19
Release date:2017-05-03
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Split luciferase-based biosensors for characterizing EED binders
Anal. Biochem., 522, 2017
5ZBM
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BU of 5zbm by Molmil
Structure of glycolate oxidase containing FMN from Nicotiana benthamiana
Descriptor: FLAVIN MONONUCLEOTIDE, Glycolate oxidase
Authors:Chen, Z, Liu, Y.
Deposit date:2018-02-12
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of glycolate oxidase from Nicotiana benthamiana reveal a conserved pH sensor affecting the binding of FMN.
Biochem.Biophys.Res.Commun., 503, 2018
5Z0Y
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BU of 5z0y by Molmil
Crystallization and structure determination of cytoplasm serine hydroxymethyltransferase (SHMT) from Pichia pastoris
Descriptor: GLYCEROL, Serine hydroxymethyltransferase
Authors:Chen, Z, Zhang, M.
Deposit date:2017-12-22
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and function of cytoplasmic serine hydroxymethyltransferase from Pichia pastoris
Biochem. Biophys. Res. Commun., 496, 2018
7VVU
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BU of 7vvu by Molmil
NuA4 HAT module bound to the nucleosome
Descriptor: CARBOXYMETHYL COENZYME *A, Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, ...
Authors:Chen, Z, Qu, K.
Deposit date:2021-11-09
Release date:2022-08-10
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022

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