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6V3N
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BU of 6v3n by Molmil
Crystal structure of CDYL2 in complex with H3K27me3
Descriptor: ACE-GLN-LEU-ALA-THR-LYS-ALA-ALA-ARG-M3L-SER-ALA-PRO-ALA-THR-TYR-NH2, Chromodomain Y-like protein 2, UNKNOWN ATOM OR ION
Authors:Qin, S, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2019-11-26
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
6V41
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BU of 6v41 by Molmil
crystal structure of CDY1 chromodomain bound to H3K9me3
Descriptor: Histone H3.1 Peptide, Testis-specific chromodomain protein Y 1, UNKNOWN ATOM OR ION
Authors:Qin, S, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2019-11-27
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
6V8W
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BU of 6v8w by Molmil
CDYL2 chromodomain in complex with a synthetic peptide
Descriptor: Chromodomain Y-like protein 2, IVA-PHE-ALA-PHE-5T3-SER-NH2, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, James, L.I, Lamb, K.N, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2019-12-12
Release date:2020-01-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
6ILP
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BU of 6ilp by Molmil
Cryo-EM structure of full Echovirus 6 particle at PH 7.4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F, Liu, S, Zhao, X, Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILN
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BU of 6iln by Molmil
Cryo-EM structure of full Echovirus 6 particle at PH 5.5
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F, Liu, S, Zhao, X, Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILK
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BU of 6ilk by Molmil
Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 7.4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F, Liu, S, Zhao, X, Peng, R.
Deposit date:2018-10-18
Release date:2019-05-15
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
7KN3
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BU of 7kn3 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ...
Authors:Liu, H, Zhu, X, Wilson, I.A.
Deposit date:2020-11-04
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
7KN4
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BU of 7kn4 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-E6 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S-E6 Fab heavy chain, S-E6 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2020-11-04
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
6S3D
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BU of 6s3d by Molmil
Structure of D25 Fab in complex with scaffold S0_2.126
Descriptor: Heavy Chain, Light Chain, S0_2.126
Authors:Cramer, J.T, Krey, T.
Deposit date:2019-06-25
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Science, 368, 2020
6S8B
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BU of 6s8b by Molmil
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1
Descriptor: CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-07-09
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
6S91
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BU of 6s91 by Molmil
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2
Descriptor: CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-07-11
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
3JSG
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BU of 3jsg by Molmil
Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 707 at 1.58a resolution
Descriptor: 7-(pyridin-3-ylmethyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION
Authors:Mclean, L, Zhang, Y.
Deposit date:2009-09-10
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening.
Bioorg.Med.Chem.Lett., 19, 2009
6S8E
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BU of 6s8e by Molmil
Cryo-EM structure of the type III-B Cmr-beta complex bound to non-cognate target RNA
Descriptor: CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-07-09
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
6SH8
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BU of 6sh8 by Molmil
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2, in the presence of ssDNA
Descriptor: CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-08-06
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
3JTU
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BU of 3jtu by Molmil
Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 708 at 1.86a resolution
Descriptor: 7-(pyridin-2-ylmethyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION
Authors:Mclean, L, Zhang, Y.
Deposit date:2009-09-14
Release date:2009-11-10
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening.
Bioorg.Med.Chem.Lett., 19, 2009
6SHB
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BU of 6shb by Molmil
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1, in the presence of ssDNA
Descriptor: CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-08-06
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
3JSF
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BU of 3jsf by Molmil
Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 638 at 1.93a resolution
Descriptor: 7-(2-fluorobenzyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION
Authors:Mclean, L, Zhang, Y.
Deposit date:2009-09-10
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening.
Bioorg.Med.Chem.Lett., 19, 2009
6S6B
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BU of 6s6b by Molmil
Type III-B Cmr-beta Cryo-EM structure of the Apo state
Descriptor: CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-07-02
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
7VLN
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BU of 7vln by Molmil
NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound
Descriptor: 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2
Authors:Cao, D.Y, Li, Y.L, Li, J, Xiong, B.
Deposit date:2021-10-05
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
J.Med.Chem., 65, 2022
6SIC
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BU of 6sic by Molmil
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA
Descriptor: CRISPR-associated RAMP protein, Cmr1 family, Cmr4 family, ...
Authors:Sofos, N, Montoya, G, Stella, S.
Deposit date:2019-08-09
Release date:2020-07-08
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Mol.Cell, 79, 2020
2MXB
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BU of 2mxb by Molmil
Structure of the transmembrane domain of the mouse erythropoietin receptor
Descriptor: Erythropoietin receptor
Authors:Li, Q, Wong, Y, Lee, M, Kang, C.
Deposit date:2014-12-19
Release date:2015-09-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles.
Sci Rep, 5, 2015
1K94
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BU of 1k94 by Molmil
Crystal structure of des(1-52)grancalcin with bound calcium
Descriptor: CALCIUM ION, GRANCALCIN
Authors:Jia, J, Borregaard, N, Lollike, K, Cygler, M.
Deposit date:2001-10-26
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Ca(2+)-loaded human grancalcin.
Acta Crystallogr.,Sect.D, 57, 2001
1K95
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BU of 1k95 by Molmil
Crystal structure of des(1-52)grancalcin with bound calcium
Descriptor: GRANCALCIN
Authors:Jia, J, Borregaard, N, Lollike, K, Cygler, M.
Deposit date:2001-10-26
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Ca(2+)-loaded human grancalcin.
Acta Crystallogr.,Sect.D, 57, 2001
4FVD
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BU of 4fvd by Molmil
Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate
Descriptor: 10-mer peptide from 2A proteinase, 2A proteinase, ZINC ION
Authors:Cai, Q, Muhammad, Y, Liu, W, Gao, Z, Peng, X, Cai, Y, Wu, C, Zheng, Q, Li, J, Lin, T.
Deposit date:2012-06-29
Release date:2013-06-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
4FVB
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BU of 4fvb by Molmil
Crystal structure of EV71 2A proteinase C110A mutant
Descriptor: 2A proteinase, ZINC ION
Authors:Cai, Q, Muhammad, Y, Liu, W, Gao, Z, Peng, X, Cai, Y, Wu, C, Zheng, Q, Li, J, Lin, T.
Deposit date:2012-06-29
Release date:2013-06-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013

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