6SHB
Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1, in the presence of ssDNA
Summary for 6SHB
Entry DOI | 10.2210/pdb6shb/pdb |
EMDB information | 10117 10196 10197 |
Descriptor | CRISPR-associated protein, Cmr5 family, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | crispr-cas, effector complex, nuclease, cyclic oligo-adenylate synthase, antiviral protein |
Biological source | Sulfolobus islandicus REY15A More |
Total number of polymer chains | 39 |
Total formula weight | 974077.80 |
Authors | Sofos, N.,Montoya, G.,Stella, S. (deposition date: 2019-08-06, release date: 2020-07-08, Last modification date: 2020-09-16) |
Primary citation | Sofos, N.,Feng, M.,Stella, S.,Pape, T.,Fuglsang, A.,Lin, J.,Huang, Q.,Li, Y.,She, Q.,Montoya, G. Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79:741-757.e7, 2020 Cited by PubMed: 32730741DOI: 10.1016/j.molcel.2020.07.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.07 Å) |
Structure validation
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