4FVD

Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate

Summary for 4FVD

• Entry DOI: 10.2210/pdb4fvd/pdb
• Related: 4FVB 4FVE 4FVH 4FVI
• Descriptor: 2A proteinase, 10-mer peptide from 2A proteinase, ZINC ION, ... (4 entities in total)
• Functional Keywords: hydrolase, cysteine proteinase, hydrolase-hydrolase substrate complex, hydrolase/hydrolase substrate
• Biological source: Human enterovirus 71; More
• Cellular location: Picornain 3C: Host cytoplasm (By similarity). Protein 3B: Virion (By similarity): A9XG43 A9XG43
• Total number of polymer chains: 2
• Total formula weight: 17753.08

Authors

Cai, Q.,Muhammad, Y.,Liu, W.,Gao, Z.,Peng, X.,Cai, Y.,Wu, C.,Zheng, Q.,Li, J.,Lin, T. (deposition date: 2012-06-29, release date: 2013-06-19, Last modification date: 2023-11-08)

• Primary citation: Cai, Q.,Yameen, M.,Liu, W.,Gao, Z.,Li, Y.,Peng, X.,Cai, Y.,Wu, C.,Zheng, Q.,Li, J.,Lin, T.; Conformational Plasticity of 2A Proteinase from Enterovirus 71; J.Virol., 87:7348-7356, 2013; PubMed: 23616646; DOI: 10.1128/JVI.03541-12

Experimental method

X-RAY DIFFRACTION (1.66 Å)