4FVD
Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2A proteinase | polymer | 152 | 16706.5 | 1 | UniProt (A9XG43) Pfam (PF00947) | Human enterovirus 71 | |
| 2 | B (C) | 10-mer peptide from 2A proteinase | polymer | 10 | 981.1 | 1 | UniProt (A9XG43) | Human enterovirus 71 | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 1 - 150 (UniProt: A9XG43)
C: -3 - 4 (UniProt: A9XG43)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 110 | Cys 972 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 17687.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 17753.1 |
