6S8B

Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1

Summary for 6S8B

• Entry DOI: 10.2210/pdb6s8b/pdb
• EMDB information: 10117
• Descriptor: CRISPR-associated protein, Cmr5 family, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (12 entities in total)
• Functional Keywords: crispr-cas, effector complex, nuclease, cyclic oligo-adenylate synthase, antiviral protein
• Biological source: Sulfolobus islandicus (strain REY15A); More
• Total number of polymer chains: 35
• Total formula weight: 895255.37

Authors

Sofos, N.,Montoya, G.,Stella, S. (deposition date: 2019-07-09, release date: 2020-07-08, Last modification date: 2020-09-16)

• Primary citation: Sofos, N.,Feng, M.,Stella, S.,Pape, T.,Fuglsang, A.,Lin, J.,Huang, Q.,Li, Y.,She, Q.,Montoya, G.; Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.; Mol.Cell, 79:741-757.e7, 2020; PubMed: 32730741; DOI: 10.1016/j.molcel.2020.07.008

Experimental method

ELECTRON MICROSCOPY (2.41 Å)