5AO4
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8PI1
| Bicyclic INCYPRO Pseudomonas fluorescens esterase | Descriptor: | Arylesterase, GLYCEROL, N-[2-[3,5-bis[2-(2-iodanylethanoylamino)ethanoyl]-1,3,5-triazinan-1-yl]-2-oxidanylidene-ethyl]-2-iodanyl-ethanamide | Authors: | Kiehstaller, S, Pearce, N.M, Grossmann, T.N, Hennig, S. | Deposit date: | 2023-06-20 | Release date: | 2023-11-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Covalent bicyclization of protein complexes yields durable quaternary structures. Chem, 10, 2024
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7AH3
| Kinase domain of cSrc in complex with a pyrazolopyrimidine | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Dello Iacono, L, Kleinboelting, S, Fallacara, A.L, Rauh, D. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Insights into the binding of pyrazolopyrimidines to Src kinase To Be Published
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1ZXJ
| Crystal structure of the hypthetical Mycoplasma protein, MPN555 | Descriptor: | Hypothetical protein MG377 homolog | Authors: | Schulze-Gahmen, U, Aono, S, Shengfeng, C, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2005-06-08 | Release date: | 2005-07-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function. Acta Crystallogr.,Sect.D, 61, 2005
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3JVF
| Crystal structure of an Interleukin-17 receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Ely, L.K, Garcia, K.C. | Deposit date: | 2009-09-16 | Release date: | 2009-10-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of receptor sharing by interleukin 17 cytokines. Nat.Immunol., 10, 2009
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7E24
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7E28
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8OWZ
| Crystal structure of human Sirt2 in complex with a triazole-based SirReal | Descriptor: | (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[5-[[3-[[1-(2-methoxyethyl)-1,2,3-triazol-4-yl]methoxy]phenyl]methyl]-1,3-thiazol-2-yl]ethanamide, ... | Authors: | Friedrich, F, Zhang, L, Schiedel, M, Einsle, O, Jung, M. | Deposit date: | 2023-04-28 | Release date: | 2023-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J.Med.Chem., 66, 2023
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6FIB
| Structure of human 4-1BB ligand | Descriptor: | Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor ligand superfamily member 9,4-1BBL -CH/CL fusion, Tumor necrosis factor ligand superfamily member 9,Uncharacterized protein | Authors: | Joseph, C, Claus, C, Ferrara, C, von Hirschheydt, T, Prince, C, Funk, D, Klein, C, Benz, J. | Deposit date: | 2018-01-17 | Release date: | 2019-03-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy. Sci Transl Med, 11, 2019
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7RX2
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7RXA
| afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+ | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase | Authors: | Feng, Z, Accardi, A. | Deposit date: | 2021-08-22 | Release date: | 2022-05-18 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13, 2022
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7RXB
| afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+ | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase | Authors: | Feng, Z, Accardi, A. | Deposit date: | 2021-08-22 | Release date: | 2022-05-18 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13, 2022
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7RXH
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7RX3
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7RXG
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7RWJ
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6PC1
| Crystal structure of Helicobacter pylori PPX/GppA (E143A) in complex with ppGpp | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PC0
| Crystal structure of Helicobacter pylori PPX/GppA | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, D-MALATE, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PBZ
| Crystal structure of Escherichia coli GppA | Descriptor: | CHLORIDE ION, Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase | Authors: | Song, H, Shaw, G.X, Wang, C, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.475 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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8P9V
| Crystal Structure of Two-Domain Laccase mutant M199G/R240H/D268N from Streptomyces griseoflavus | Descriptor: | COPPER (II) ION, OXYGEN MOLECULE, PEROXIDE ION, ... | Authors: | Kolyadenko, I.A, Tishchenko, S.V, Gabdulkhakov, A.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Insight into the Amino Acid Environment of the Two-Domain Laccase's Trinuclear Copper Cluster. Int J Mol Sci, 24, 2023
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8P9U
| Crystal Structure of Two-Domain Laccase mutant M199A/D268N from Streptomyces griseoflavus | Descriptor: | CALCIUM ION, COPPER (II) ION, OXYGEN MOLECULE, ... | Authors: | Kolyadenko, I.A, Tishchenko, S.V, Gabdulkhakov, A.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insight into the Amino Acid Environment of the Two-Domain Laccase's Trinuclear Copper Cluster. Int J Mol Sci, 24, 2023
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8OX0
| Structure of apo telomeric nucleosome | Descriptor: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | Authors: | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | Deposit date: | 2023-04-28 | Release date: | 2023-08-30 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1. Sci Adv, 9, 2023
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8OX1
| Structure of TRF1core in complex with telomeric nucleosome | Descriptor: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | Authors: | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | Deposit date: | 2023-04-28 | Release date: | 2023-08-30 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1. Sci Adv, 9, 2023
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6VYD
| Terpenoid Cyclase FgGS in Complex with Mg, Inorganic Pyrophosphate, and Benzyltriethylammonium cation | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Herbst-Gervasoni, C.J, Christianson, D.W. | Deposit date: | 2020-02-26 | Release date: | 2020-07-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases. Nat Commun, 11, 2020
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6W26
| Terpenoid Cyclase FgGS in Complex with Mg, Inorganic Pyrophosphate, and Imidazole | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, IMIDAZOLE, ... | Authors: | Herbst-Gervasoni, C.J, Christianson, D.W. | Deposit date: | 2020-03-05 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases. Nat Commun, 11, 2020
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