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8T0E
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BU of 8t0e by Molmil
TRPV1 in Nanodisc not bound with lysophosphatidic acid (apo)
Descriptor: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
Authors:Arnold, W.R, Cheng, Y.
Deposit date:2023-05-31
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T0Y
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BU of 8t0y by Molmil
TRPV1 in nanodisc bound with one LPA in one monomer
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ...
Authors:Arnold, W.R, Cheng, Y.
Deposit date:2023-06-01
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
6UTG
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BU of 6utg by Molmil
Allosteric coupling between alpha-rings of the 20S proteasome, 20S singly capped with a PA26/V230F
Descriptor: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
Authors:Yu, Z, Cheng, Y.
Deposit date:2019-10-29
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
2B34
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BU of 2b34 by Molmil
Structure of MAR1 Ribonuclease from Caenorhabditis elegans
Descriptor: MAR1 Ribonuclease
Authors:Schormann, N, Karpova, E, Li, S, Symersky, J, Zhang, Y, Lu, S, Zhou, Q, Lin, G, Cao, Z, Luo, M, Qiu, S, Luan, C.-H, Luo, D, Huang, W, Shang, Q, McKinstry, A, An, J, Tsao, J, Carson, M, Stinnett, M, Chen, Y, Johnson, D, Gary, R, Arabshahi, A, Bunzel, R, Bray, T, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-09-19
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structure of MAR1 Ribonuclease from Caenorhabditis elegans
To be Published
8W6D
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BU of 8w6d by Molmil
CryoEM structure of NaDC1 in apo state
Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
Authors:Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R.
Deposit date:2023-08-28
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism.
Sci Adv, 10, 2024
8W6N
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BU of 8w6n by Molmil
NaS1 with sulfate in IN/OUT state
Descriptor: SODIUM ION, SULFATE ION, Solute carrier family 13 member 1
Authors:Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R.
Deposit date:2023-08-29
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism.
Sci Adv, 10, 2024
8W6O
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BU of 8w6o by Molmil
NaS1 in IN/IN state
Descriptor: CHOLESTEROL, SODIUM ION, Solute carrier family 13 member 1
Authors:Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R.
Deposit date:2023-08-29
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism.
Sci Adv, 10, 2024
5XP5
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BU of 5xp5 by Molmil
C-Src in complex with ATP-Chf
Descriptor: MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-[(S)-fluoranyl-[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid
Authors:Duan, Y, Guo, M, Dai, S, Chen, L, Chen, Y.
Deposit date:2017-06-01
Release date:2018-02-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
4OI3
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BU of 4oi3 by Molmil
Crystal structure analysis of SCO4226 from Streptomyces coelicolor A3(2)
Descriptor: Nickel responsive protein
Authors:Lu, M, Jiang, Y.L, Wang, S, Cheng, W, Zhang, R.G, Virolle, M.J, Chen, Y, Zhou, C.Z.
Deposit date:2014-01-18
Release date:2014-09-17
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Streptomyces coelicolor SCO4226 Is a Nickel Binding Protein.
Plos One, 9, 2014
1ZKL
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BU of 1zkl by Molmil
Multiple Determinants for Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases
Descriptor: 3-ISOBUTYL-1-METHYLXANTHINE, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ...
Authors:Wang, H, Liu, Y, Chen, Y, Robinson, H, Ke, H.
Deposit date:2005-05-03
Release date:2005-07-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7
J.Biol.Chem., 280, 2005
4RDJ
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BU of 4rdj by Molmil
Crystal structure of Norovirus Boxer P domain
Descriptor: Capsid
Authors:Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
3EY8
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BU of 3ey8 by Molmil
Structure from the mobile metagenome of V. Pseudocholerae. VPC_CASS1
Descriptor: Biphenyl-2,3-diol 1,2-dioxygenase III-related protein, SULFATE ION
Authors:Harrop, S.J, Deshpande, C.N, Sureshan, V, Boucher, Y, Xu, X, Cui, H, Chang, C, Edwards, A, Joachimiak, A, Savchenko, A, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-10-20
Release date:2009-01-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure from the mobile metagenome of V. Pseudocholerae. VPC_CASS1
To be Published
4QSG
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BU of 4qsg by Molmil
Crystal structure of gas vesicle protein GvpF from Microcystis aeruginosa
Descriptor: Gas vesicle protein
Authors:Xu, B.Y, Dai, Y.N, Zhou, K, Ren, Y.M, Liu, Y.T, Chen, Y, Zhou, C.Z.
Deposit date:2014-07-03
Release date:2014-11-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the gas vesicle protein GvpF from the cyanobacterium Microcystis aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4RDL
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BU of 4rdl by Molmil
Crystal structure of Norovirus Boxer P domain in complex with Lewis y tetrasaccharide
Descriptor: Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
4RDK
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BU of 4rdk by Molmil
Crystal structure of Norovirus Boxer P domain in complex with Lewis b tetrasaccharide
Descriptor: Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
1JJR
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BU of 1jjr by Molmil
The Three-Dimensional Structure of the C-terminal DNA Binding Domain of Human Ku70
Descriptor: THYROID AUTOANTIGEN
Authors:Zhang, Z, Chen, Y.
Deposit date:2001-07-09
Release date:2001-10-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70.
J.Biol.Chem., 276, 2001
4C0F
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BU of 4c0f by Molmil
Structure of the NOT-box domain of human CNOT2
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2
Authors:Boland, A, Chen, Y, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2013-08-01
Release date:2013-10-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
4Z8I
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BU of 4z8i by Molmil
Crystal structure of Branchiostoma belcheri tsingtauense peptidoglycan recognition protein 3
Descriptor: ZINC ION, peptidoglycan recognition protein 3
Authors:Wang, W.J, Cheng, W, Jiang, Y.L, Luo, M, Cao, D.D, Chi, C.B, Yang, H.B, Chen, Y, Zhou, C.Z.
Deposit date:2015-04-09
Release date:2015-10-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Activity Augmentation of Amphioxus Peptidoglycan Recognition Protein BbtPGRP3 via Fusion with a Chitin Binding Domain
Plos One, 10, 2015
3G1J
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BU of 3g1j by Molmil
Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS4.
Descriptor: Integron cassette protein
Authors:Deshpande, C.N, Sureshan, V, Harrop, S.J, Boucher, Y, Xu, X, Cui, H, Edwards, A, Savchenko, A, Joachimiak, A, Tan, K, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-01-30
Release date:2009-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS4.
To be published
4UA7
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BU of 4ua7 by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-benzimidazole-4-carboxamide, PHOSPHATE ION
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.89 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
4UA9
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BU of 4ua9 by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with a Boronic Acid Acylation Transition State Analog at Sub-Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.84 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
4UA6
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BU of 4ua6 by Molmil
CTX-M-14 Class A Beta-Lactamase Apo Crystal Structure at 0.79 Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, PHOSPHATE ION, POTASSIUM ION
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
7US2
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BU of 7us2 by Molmil
PARL-cleaved Skd3 (human ClpB) E455Q Nucleotide Binding Domain hexamer bound to ATPgammaS, open conformation
Descriptor: Caseinolytic peptidase B protein homolog, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Gupta, A, Lentzsch, A.M, Siegel, A.S, Yu, Z, Lu, C, Chio, U.S, Cheng, Y, Shan, S.-o.
Deposit date:2022-04-22
Release date:2023-04-26
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Dodecamer assembly of a metazoan AAA + chaperone couples substrate extraction to refolding.
Sci Adv, 9, 2023
5WSU
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BU of 5wsu by Molmil
Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM
Descriptor: Calmodulin, Unconventional myosin-VIIa
Authors:Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M.
Deposit date:2016-12-08
Release date:2017-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
4UAA
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BU of 4uaa by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-benzimidazole-4-carboxamide, PHOSPHATE ION
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.86 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015

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