7US2

PARL-cleaved Skd3 (human ClpB) E455Q Nucleotide Binding Domain hexamer bound to ATPgammaS, open conformation

Summary for 7US2

• Entry DOI: 10.2210/pdb7us2/pdb
• EMDB information: 26722 26725 26726 26728
• Descriptor: Caseinolytic peptidase B protein homolog, Substrate, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: aaa+ atpase, chaperone, mitochondria, protein folding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 399972.09

Authors

Gupta, A.,Lentzsch, A.M.,Siegel, A.S.,Yu, Z.,Lu, C.,Chio, U.S.,Cheng, Y.,Shan, S.-o. (deposition date: 2022-04-22, release date: 2023-04-26, Last modification date: 2023-11-08)

• Primary citation: Gupta, A.,Lentzsch, A.M.,Siegel, A.,Yu, Z.,Chio, U.S.,Cheng, Y.,Shan, S.O.; Dodecamer assembly of a metazoan AAA + chaperone couples substrate extraction to refolding.; Sci Adv, 9:eadf5336-eadf5336, 2023; PubMed: 37163603; DOI: 10.1126/sciadv.adf5336

Experimental method

ELECTRON MICROSCOPY (2.76 Å)