8T0E
TRPV1 in Nanodisc not bound with lysophosphatidic acid (apo)
Summary for 8T0E
| Entry DOI | 10.2210/pdb8t0e/pdb |
| EMDB information | 40941 |
| Descriptor | Transient receptor potential cation channel subfamily V member 1, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ... (4 entities in total) |
| Functional Keywords | trpv1, lysophosphatidic acid, membrane protein |
| Biological source | Rattus norvegicus (Norway rat) |
| Total number of polymer chains | 4 |
| Total formula weight | 374108.23 |
| Authors | Arnold, W.R.,Cheng, Y. (deposition date: 2023-05-31, release date: 2024-05-08, Last modification date: 2024-05-15) |
| Primary citation | Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38698206DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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