1ZP0
 
 | | Crystal Structure of Mitochondrial Respiratory Complex II bound with 3-nitropropionate and 2-thenoyltrifluoroacetone | | Descriptor: | 3-NITROPROPANOIC ACID, 4,4,4-TRIFLUORO-1-THIEN-2-YLBUTANE-1,3-DIONE, FAD-binding protein, ... | | Authors: | Sun, F, Huo, X, Zhai, Y, Wang, A, Xu, J, Su, D, Bartlam, M, Rao, Z. | | Deposit date: | 2005-05-16 | | Release date: | 2005-07-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II
Cell(Cambridge,Mass.), 121, 2005
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2GTI
 | | mutation of MHV coronavirus non-structural protein nsp15 (F307L) | | Descriptor: | GLYCEROL, Replicase polyprotein 1ab, SULFATE ION | | Authors: | Xu, X, Zhai, Y, Sun, F, Lou, Z, Su, D, Rao, Z. | | Deposit date: | 2006-04-28 | | Release date: | 2006-08-15 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
J.Virol., 80, 2006
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2GTH
 | | crystal structure of the wildtype MHV coronavirus non-structural protein nsp15 | | Descriptor: | Replicase polyprotein 1ab | | Authors: | Xu, X, Zhai, Y, Sun, F, Lou, Z, Su, D, Rao, Z. | | Deposit date: | 2006-04-28 | | Release date: | 2006-08-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
J.Virol., 80, 2006
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5JQL
 | | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 2.9 Angstroms Resolution | | Descriptor: | Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial | | Authors: | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | | Deposit date: | 2016-05-05 | | Release date: | 2017-07-12 | | Last modified: | 2020-09-02 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1
Commun Biol, 2020
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5JQM
 | | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 1.5 Angstroms Resolution | | Descriptor: | Protein UPS1, mitochondrial,Mitochondrial distribution and morphology protein 35 | | Authors: | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | | Deposit date: | 2016-05-05 | | Release date: | 2017-07-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1
Commun Biol, 2020
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8K4Y
 | | Structure of a triple-helix region of human ReCol 3 from Trautec | | Descriptor: | SULFATE ION, triple-helix region of human ReCol 3 | | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | Deposit date: | 2023-07-20 | | Release date: | 2023-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a triple-helix region of human ReCol 3 from Trautec.
To Be Published
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8K4X
 | | Structure of a triple-helix region of human Collagen type XVII from Trautec | | Descriptor: | triple-helix region of human Collagen type XVII | | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | Deposit date: | 2023-07-20 | | Release date: | 2023-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec.
To Be Published
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8K4W
 | | Structure of a triple-helix region of human collagen type I from Trautec | | Descriptor: | CHLORIDE ION, triple-helix region of human collagen type I | | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | | Deposit date: | 2023-07-20 | | Release date: | 2023-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a triple-helix region of human collagen type I from Trautec.
To Be Published
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2GA6
 | | The crystal structure of SARS nsp10 without zinc ion as additive | | Descriptor: | ZINC ION, orf1a polyprotein | | Authors: | Su, D, Lou, Z, Sun, F, Zhai, Y, Yang, H, Rao, Z. | | Deposit date: | 2006-03-08 | | Release date: | 2006-08-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
J.Virol., 80, 2006
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3A8Q
 | | Low-resolution crystal structure of the Tiam2 PHCCEx domain | | Descriptor: | T-lymphoma invasion and metastasis-inducing protein 2 | | Authors: | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 2009-10-07 | | Release date: | 2009-11-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
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3A8P
 | | Crystal structure of the Tiam2 PHCCEx domain | | Descriptor: | T-lymphoma invasion and metastasis-inducing protein 2 | | Authors: | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 2009-10-07 | | Release date: | 2009-11-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
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3A8N
 | | Crystal structure of the Tiam1 PHCCEx domain | | Descriptor: | T-lymphoma invasion and metastasis-inducing protein 1 | | Authors: | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 2009-10-07 | | Release date: | 2009-11-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
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4HNE
 | | Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase (PI4KIIalpha) in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase type 2-alpha | | Authors: | Zhou, Q, Zhai, Y, Zhang, K, Chen, C, Sun, F. | | Deposit date: | 2012-10-19 | | Release date: | 2014-04-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Molecular insights into the membrane-associated phosphatidylinositol 4-kinase II alpha.
Nat Commun, 5, 2014
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7W1Y
 | | Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (49-MER), ... | | Authors: | Li, J, Dong, J, Dang, S, Zhai, Y. | | Deposit date: | 2021-11-21 | | Release date: | 2023-02-08 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.59 Å) | | Cite: | The human pre-replication complex is an open complex.
Cell, 186, 2023
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3A2A
 | | The structure of the carboxyl-terminal domain of the human voltage-gated proton channel Hv1 | | Descriptor: | CHLORIDE ION, Voltage-gated hydrogen channel 1 | | Authors: | Li, S.J, Unno, H, Zhou, Q, Zhao, Q, Zhai, Y, Sun, F. | | Deposit date: | 2009-05-08 | | Release date: | 2010-02-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The role and structure of the carboxyl-terminal domain of the human voltage-gated proton channel Hv1.
J.Biol.Chem., 285, 2010
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7V3U
 | | Cryo-EM structure of MCM double hexamer with structured Mcm4-NSD | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | | Authors: | Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. | | Deposit date: | 2021-08-11 | | Release date: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
Nat Commun, 13, 2022
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7V3V
 | | Cryo-EM structure of MCM double hexamer bound with DDK in State I | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ... | | Authors: | Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. | | Deposit date: | 2021-08-11 | | Release date: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
Nat Commun, 13, 2022
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7W8G
 | | Cryo-EM structure of MCM double hexamer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | | Authors: | Cheng, J, Li, N, Tye, B, Zhai, Y, Gao, N. | | Deposit date: | 2021-12-07 | | Release date: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
Nat Commun, 13, 2022
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7CTG
 | | Human Origin Recognition Complex, ORC1-5 State I | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | | Deposit date: | 2020-08-18 | | Release date: | 2021-01-06 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
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7CTF
 | | Human origin recognition complex 1-5 State II | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | | Deposit date: | 2020-08-18 | | Release date: | 2021-01-06 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
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7CTE
 | | Human Origin Recognition Complex, ORC2-5 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ... | | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | | Deposit date: | 2020-08-18 | | Release date: | 2021-01-06 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
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5BPE
 | | Crystal structure of EV71 3Cpro in complex with a potent and selective Inhibitor | | Descriptor: | (2~{S})-~{N}-[(1~{R},2~{S})-1-cyano-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-3-phenyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanamide, EV71 3Cpro | | Authors: | Luqing, S, Yin, Z. | | Deposit date: | 2015-05-28 | | Release date: | 2015-11-25 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease
J.Med.Chem., 58, 2015
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7Y04
 | | Hsp90-AhR-p23 complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | | Deposit date: | 2022-06-03 | | Release date: | 2023-01-04 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
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8H77
 | | Hsp90-AhR-p23-XAP2 complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | | Deposit date: | 2022-10-19 | | Release date: | 2023-01-04 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
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4Y9L
 | | Crystal Structure of Caenorhabditis elegans ACDH-11 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Protein ACDH-11, isoform b | | Authors: | Li, Z.J, Zhai, Y.J, Zhang, K, Sun, F. | | Deposit date: | 2015-02-17 | | Release date: | 2015-06-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids
Cell, 161, 2015
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