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4HNE

Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase (PI4KIIalpha) in complex with ADP

Summary for 4HNE
Entry DOI10.2210/pdb4hne/pdb
Related4HND
DescriptorPhosphatidylinositol 4-kinase type 2-alpha, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywordspi3k/pi4k kinase, lipid kinase, atp binding, palmitoylation, membrane anchoring, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q9BTU6
Total number of polymer chains2
Total formula weight88504.16
Authors
Zhou, Q.,Zhai, Y.,Zhang, K.,Chen, C.,Sun, F. (deposition date: 2012-10-19, release date: 2014-04-09, Last modification date: 2023-09-20)
Primary citationZhou, Q.,Li, J.,Yu, H.,Zhai, Y.,Gao, Z.,Liu, Y.,Pang, X.,Zhang, L.,Schulten, K.,Sun, F.,Chen, C.
Molecular insights into the membrane-associated phosphatidylinositol 4-kinase II alpha.
Nat Commun, 5:3552-3552, 2014
Cited by
PubMed: 24675427
DOI: 10.1038/ncomms4552
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

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