4HNE
Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase (PI4KIIalpha) in complex with ADP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Phosphatidylinositol 4-kinase type 2-alpha | polymer | 384 | 43824.9 | 2 | UniProt (Q9BTU6) Pfam (PF00454) In PDB | Homo sapiens (human) | Phosphatidylinositol 4-kinase type II-alpha |
2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
3 | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B: 78 - 453 (UniProt: Q9BTU6)
PDB | External Database | Details |
---|---|---|
Gly 70 | - | expression tag |
Pro 71 | - | expression tag |
Leu 72 | - | expression tag |
Gly 73 | - | expression tag |
Ser 74 | - | expression tag |
Pro 75 | - | expression tag |
Glu 76 | - | expression tag |
Phe 77 | - | expression tag |
Ser 174 | Cys 174 | engineered mutation |
Ser 175 | Cys 175 | engineered mutation |
Ser 177 | Cys 177 | engineered mutation |
Ser 178 | Cys 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 87649.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 854.4 | |
All* | Total formula weight | 88504.2 |