7V3V

Cryo-EM structure of MCM double hexamer bound with DDK in State I

This is a non-PDB format compatible entry.

Summary for 7V3V

• Entry DOI: 10.2210/pdb7v3v/pdb
• EMDB information: 31685
• Descriptor: DNA replication licensing factor MCM2, MAGNESIUM ION, ZINC ION, ... (12 entities in total)
• Functional Keywords: kinase, replicative helicase, complex, replication, cell cycle
• Biological source: Saccharomyces cerevisiae S288C; More
• Total number of polymer chains: 14
• Total formula weight: 1359575.05

Authors

Cheng, J.,Li, N.,Huo, Y.,Dang, S.,Tye, B.,Gao, N.,Zhai, Y. (deposition date: 2021-08-11, release date: 2022-04-13)

• Primary citation: Cheng, J.,Li, N.,Huo, Y.,Dang, S.,Tye, B.K.,Gao, N.,Zhai, Y.; Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.; Nat Commun, 13:1396-1396, 2022; PubMed: 35296675; DOI: 10.1038/s41467-022-29070-5

Experimental method

ELECTRON MICROSCOPY (2.9 Å)