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7V3V

Cryo-EM structure of MCM double hexamer bound with DDK in State I

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, G
(2, B)
DNA replication licensing factor MCM2polymer86898911.52UniProt (P29469)
Pfam (PF12619)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Saccharomyces cerevisiae S288CMinichromosome maintenance protein 2
2B, H
(3, C)
DNA replication licensing factor MCM3polymer971107653.52UniProt (P24279)
Pfam (PF22207)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Saccharomyces cerevisiae S288CMinichromosome maintenance protein 3
3C, I
(4, D)
DNA replication licensing factor MCM4polymer933105138.42UniProt (P30665)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Pfam (PF21128)
Saccharomyces cerevisiae S288CCell division control protein 54
4D, J
(5, E)
Minichromosome maintenance protein 5polymer77586505.72UniProt (P29496)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Pfam (PF21933)
Saccharomyces cerevisiae S288CCell division control protein 46
5E, K
(6, F)
DNA replication licensing factor MCM6polymer1017113110.22UniProt (P53091)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Pfam (PF18263)
Saccharomyces cerevisiae S288CMinichromosome maintenance protein 6
6F, L
(7, G)
DNA replication licensing factor MCM7polymer84595049.92UniProt (P38132)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Saccharomyces cerevisiae S288CCell division control protein 47,Minichromosome maintenance protein 7
7M
(H)
Cell division control protein 7polymer50758391.11UniProt (P06243)
Pfam (PF00069)
Saccharomyces cerevisiae S288C
8N
(I)
DDK kinase regulatory subunit DBF4polymer70480824.21UniProt (P32325)
Pfam (PF22437)
Pfam (PF08630)
Pfam (PF07535)
Saccharomyces cerevisiae S288CDumbbell forming protein 4
9AA, CA, FA, KA, O...
(6, 7, B, D, 2...)
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTERnon-polymer523.211Chemie (AGS)
10DA, GA, JA, LA, NA...
(7, B, C, D, 2...)
MAGNESIUM IONnon-polymer24.312Chemie (MG)
11BA, EA, HA, MA, Q...
(6, 7, B, D, 2...)
ZINC IONnon-polymer65.411Chemie (ZN)
12IA, R
(C, 3)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains14
Total formula weight1351953.8
Non-Polymers*Number of molecules36
Total formula weight7621.3
All*Total formula weight1359575.0
*Water molecules are not included.

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PDB entries from 2024-10-30

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