8KB1
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![BU of 8kb1 by Molmil](/molmil-images/mine/8kb1) | Crystal structure of 11JD | Descriptor: | Beta2-microglobulin, MHC class I antigen, peptide of AIV | Authors: | Tang, Z, Zhang, N. | Deposit date: | 2023-08-03 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
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6KX3
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![BU of 6kx3 by Molmil](/molmil-images/mine/6kx3) | Crystal structure of RhoA protein with covalent inhibitor DC-Rhoin | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA, prop-2-enyl (3R)-1,1-bis(oxidanylidene)-2,3-dihydro-1-benzothiophene-3-carboxylate | Authors: | Zhang, H, Luo, C. | Deposit date: | 2019-09-09 | Release date: | 2020-08-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion. Adv Sci, 7, 2020
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6KX2
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![BU of 6kx2 by Molmil](/molmil-images/mine/6kx2) | Crystal structure of GDP bound RhoA protein | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA | Authors: | Zhang, H, Luo, C. | Deposit date: | 2019-09-09 | Release date: | 2020-08-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.454 Å) | Cite: | Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion. Adv Sci, 7, 2020
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7C8G
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![BU of 7c8g by Molmil](/molmil-images/mine/7c8g) | Structure of alginate lyase AlyC3 | Descriptor: | Alginate lyase AlyC3, GLYCEROL, SUCCINIC ACID | Authors: | Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P. | Deposit date: | 2020-05-30 | Release date: | 2020-10-07 | Last modified: | 2020-12-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic. J.Biol.Chem., 295, 2020
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7C8F
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![BU of 7c8f by Molmil](/molmil-images/mine/7c8f) | Structure of alginate lyase AlyC3 in complex with dimannuronate(2M) | Descriptor: | H127A/Y244A mutant of alginate lyase AlyC3 in complex with dimannuronate, MALONATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P. | Deposit date: | 2020-05-30 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.461 Å) | Cite: | Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic. J.Biol.Chem., 295, 2020
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7N6W
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![BU of 7n6w by Molmil](/molmil-images/mine/7n6w) | Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U2 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, S, Wang, K, Mao, Y. | Deposit date: | 2021-06-09 | Release date: | 2021-09-22 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer. J.Virol., 95, 2021
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7N6U
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![BU of 7n6u by Molmil](/molmil-images/mine/7n6u) | Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U1 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, S, Wang, K, Mao, Y. | Deposit date: | 2021-06-09 | Release date: | 2021-09-22 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer. J.Virol., 95, 2021
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5K04
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![BU of 5k04 by Molmil](/molmil-images/mine/5k04) | The NatB Acetyltransferase Complex Bound To CoA and MES | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COENZYME A, N-terminal acetyltransferase B complex subunit NAT3, ... | Authors: | Hong, H, Cai, Y, Zhang, S, Han, A. | Deposit date: | 2016-05-17 | Release date: | 2017-04-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB Structure, 25, 2017
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5K18
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![BU of 5k18 by Molmil](/molmil-images/mine/5k18) | The NatB Acetyltransferase Complex Bound To bisubstrate inhibitor | Descriptor: | Bisubstrate inhibitor, COENZYME A, N-terminal acetyltransferase B complex subunit NAT3, ... | Authors: | Hong, H, Cai, Y, Zhang, S, Han, A. | Deposit date: | 2016-05-17 | Release date: | 2017-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB Structure, 25, 2017
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7SG4
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![BU of 7sg4 by Molmil](/molmil-images/mine/7sg4) | |
8FAE
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![BU of 8fae by Molmil](/molmil-images/mine/8fae) | Asymmetric structure of cleaved HIV-1 AE2 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles (AE2.1) | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, K, Zhang, S, Sodroski, J, Mao, Y. | Deposit date: | 2022-11-26 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric conformations of cleaved HIV-1 envelope glycoprotein trimers in styrene-maleic acid lipid nanoparticles. Commun Biol, 6, 2023
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8FAD
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![BU of 8fad by Molmil](/molmil-images/mine/8fad) | Asymmetric structure of cleaved HIV-1 AD8 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, K, Zhang, S, Sodroski, J, Mao, Y. | Deposit date: | 2022-11-26 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Asymmetric conformations of cleaved HIV-1 envelope glycoprotein trimers in styrene-maleic acid lipid nanoparticles. Commun Biol, 6, 2023
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5LOV
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![BU of 5lov by Molmil](/molmil-images/mine/5lov) | DZ-2384 tubulin complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DZ 2384, ... | Authors: | Prota, A.E, Steinmetz, M.O, Shore, G.C, Brouhard, G, Roulston, A. | Deposit date: | 2016-08-10 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. Sci Transl Med, 8, 2016
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5GUT
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![BU of 5gut by Molmil](/molmil-images/mine/5gut) | The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | Authors: | Chen, S.J, Ye, F. | Deposit date: | 2016-08-31 | Release date: | 2017-09-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
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4FD6
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![BU of 4fd6 by Molmil](/molmil-images/mine/4fd6) | |
4FD7
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![BU of 4fd7 by Molmil](/molmil-images/mine/4fd7) | Crystal structure of insect putative arylalkylamine N-Acetyltransferase 7 from the yellow fever mosquito Aedes aegypt | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, SULFATE ION, ... | Authors: | Han, Q, Robinson, R, Li, J. | Deposit date: | 2012-05-26 | Release date: | 2012-06-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evolution of insect arylalkylamine N-acetyltransferases: structural evidence from the yellow fever mosquito, Aedes aegypti. Proc.Natl.Acad.Sci.USA, 109, 2012
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3NSQ
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![BU of 3nsq by Molmil](/molmil-images/mine/3nsq) | Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron | Descriptor: | 1,8-dihydroxyanthracene-9,10-dione, Retinoid X receptor, alpha | Authors: | Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. | Deposit date: | 2010-07-02 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J.Biol.Chem., 286, 2011
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3NSP
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![BU of 3nsp by Molmil](/molmil-images/mine/3nsp) | Crystal structure of tetrameric RXRalpha-LBD | Descriptor: | Retinoid X receptor, alpha | Authors: | Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. | Deposit date: | 2010-07-02 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J.Biol.Chem., 286, 2011
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5Y1Y
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![BU of 5y1y by Molmil](/molmil-images/mine/5y1y) | |
8JI8
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![BU of 8ji8 by Molmil](/molmil-images/mine/8ji8) | Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ... | Authors: | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | Deposit date: | 2023-05-26 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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8JIB
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![BU of 8jib by Molmil](/molmil-images/mine/8jib) | Crystal Structure of Prophenoloxidase PPO6 from Aedes aegypti | Descriptor: | 1,2-ETHANEDIOL, COPPER (II) ION, TK receptor | Authors: | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | Deposit date: | 2023-05-26 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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5Z5T
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![BU of 5z5t by Molmil](/molmil-images/mine/5z5t) | The first bromodomain of BRD4 with compound BDF-2141 | Descriptor: | 2-amino-4-(1H-imidazol-1-yl)quinolin-8-ol, Bromodomain-containing protein 4 | Authors: | Zhang, H, Luo, C. | Deposit date: | 2018-01-20 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.991 Å) | Cite: | Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma. Oncogenesis, 7, 2018
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5Z5V
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![BU of 5z5v by Molmil](/molmil-images/mine/5z5v) | The first bromodomain of BRD4 with compound BDF-1253 | Descriptor: | Bromodomain-containing protein 4, N-{8-hydroxy-4-[(1H-imidazol-1-yl)methyl]quinolin-2-yl}acetamide | Authors: | Zhang, H, Luo, C. | Deposit date: | 2018-01-20 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma. Oncogenesis, 7, 2018
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5Z5U
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![BU of 5z5u by Molmil](/molmil-images/mine/5z5u) | The first bromodomain of BRD4 with compound BDF-2254 | Descriptor: | 2-amino-4-(1H-imidazol-1-yl)quinoline-6,8-diol, Bromodomain-containing protein 4 | Authors: | Zhang, H, Luo, C. | Deposit date: | 2018-01-20 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.631 Å) | Cite: | Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma. Oncogenesis, 7, 2018
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5WUU
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![BU of 5wuu by Molmil](/molmil-images/mine/5wuu) | |