5GUT

The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A

Summary for 5GUT

Entry DOI	10.2210/pdb5gut/pdb
Related	5GUV
Descriptor	DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (5 entities in total)
Functional Keywords	mutant, transferase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	100326.31
Authors	Chen, S.J.,Ye, F. (deposition date: 2016-08-31, release date: 2017-09-06, Last modification date: 2023-11-08)
Primary citation	Ye, F.,Kong, X.,Zhang, H.,Liu, Y.,Shao, Z.,Jin, J.,Cai, Y.,Zhang, R.,Li, L.,Zhang, Y.W.,Liu, Y.C.,Zhang, C.,Xie, W.,Yu, K.,Ding, H.,Zhao, K.,Chen, S.,Jiang, H.,Baylin, S.B.,Luo, C. Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13:772-781, 2018 Cited by PubMed: 29381856 DOI: 10.1021/acschembio.7b00890 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.099 Å)

Structure validation